BACKGROUNDHospital accreditation assesses hospital performance against explicit standards. Studies of the efficacy of accreditation are limited, but suggest that Joint Commission International (JCI) accreditation is efficient in improving the safety and quality of care in accredited hospitals.OBJECTIVESThis study aimed to assess the perceptions of health professionals on the impact of JCI accreditation and implementation of change towards the delivery of quality patient care.DESIGNCross-sectional survey.SETTINGSKing Abdulaziz Medical City in Jeddah, Saudi Arabia.SUBJECTSBetween June 2016 and September 2016, a validated questionnaire was distributed to physicians, nurses, medical technologists, dietitians, and other allied healthcare professionals. The questionnaire consisted of 19 items covering participation in accreditation, benefits of accreditation, and the quality of results of accreditation. Demographic data collected on the participants included age, gender, educational attainment, profession, length of service, and department.MAIN OUTCOME MEASURE(S)Participation in accreditation, benefits of accreditation, and quality of results of accreditation.RESULTSHospital accreditation was given a worthy response from the general view of 901 health professionals. The mean (standard deviation) of scores on a 5-point Likert scale were 3.79 (0.68) for participation in accreditation, 3.85 (0.84) for benefits, and 3.54 (1.01) for quality of results.CONCLUSIONAs perceived by health professionals in our survey, accrediation had a positive impact on the process and implementation of change in the hospital that resulted in improvement in the delivery of patient care and other health services.LIMITATIONSSingle institution study with no comparison made to other small, medium, or large-sized JCI-accredited hospitals in Saudi Arabia. Patient satisfaction before and after accreditation was not included.
Objective:To review and analyze the neurological complications from bariatric surgery in Kingdom of Saudi Arabia.Methods:This cross sectional study was carried out in King Abdulaziz Medical City, Jeddah, Kingdom of Saudi Arabia from January 2009 to December 2015. Important personal and clinical data were collected from the charts of the patients who underwent bariatric surgery. Data on follow up visit and remote complication if present, was also collected. All patients with neurological complications were reviewed in detail. The significant difference was calculated by using T-test and p-value<0.05 was considered significant.Results:A total of 451 patients underwent bariatric surgery, 15 cases had neurological complications (3%). Axonal polyneuropathy was the most frequent neurological complication, but cases of Wernicke syndrome, vitamin B12 deficiency, Guillain-Barre syndrome and copper deficiency were also identified. Fourteen patients (93.3%) had full recovery from the neurological signs and symptoms; one patient died.Conclusions:Bariatric surgery is not free of potential neurological complications. Complications may affect both central and peripheral nervous system and death is a possibility. Multidisciplinary care including consultation of different teams is highly recommended.
Introduction: E-learning is the use of the internet and associated devices for educational purposes without geographical constraints. This study aims to assess the perception of students at King Saud bin Abdulaziz University for Health Sciences in Jeddah, Saudi Arabia, about E-learning as a teaching modality. Methods: This cross-sectional study was conducted between June 2017 and June 2018. The inclusion criteria consisted of healthcare students (medicine, nursing, and college of sciences and health professions). A 40-item closed-ended questionnaire was distributed to the participants and was divided into six main parts: perception, diversity, implications, efficiency, acceptability, and accessibility of E-learning. Results: The response rate was 94.4% (total = 410, retrieved = 387), of which 61.8% (n = 239) stated that they had heard something about E-learning. Meanwhile, 52.2% (n = 202) of students had no idea about virtual patients. Notably, 73.1% (n = 283) agreed that cell phones can be used as a teaching modality, whereas 52.2% (n = 202) opined that cell phones can play a role in stimulating critical thinking among medical students. Sixty percent (n = 232) of students believed that E-learning has the potential to expand educational opportunities. Compared to male students, female students had a higher perception of cheating and fraud (p = 0.039) during E-learning as well as perception of a decline in personal efforts in quest of knowledge (p = 0.032). Conclusion: There is a growing positive perception of E-learning, but the level of acceptance remains low. Further research is required on how to enhance and maximize the confident utilization of ever-increasing opportunities in E-learning. Establishing well-developed E-learning facilities in Saudi educational institutions will tremendously enhance educational opportunities for its students.
The outbreak of the COVID-19 pandemic in China has become an urgent health and economic challenge. The objective of the current work was to evaluate the efficacy of the combined complex of Sitagliptin (SIT) with melittin (MEL) against SARS-CoV-2 virus. SIT-MEL nano-conjugates were optimized by a full three-factor bi-level (23) factorial design. In addition, SIT concentration (mM, X1), MEL concentration (mM, X2), and pH (X3) were selected as the critical factors. Particle size (nm, Y1) and zeta potential (mV, Y2) were assessed as responses. Characterization of the optimized formula for Fourier-transformed infrared (FTIR) was carried out. The optimized formula showed particle size and zeta potential values of 77.42 nm and 27.67 mV, respectively. When compared with SIT and MEL, the combination of SIT-MEL complex has shown anti-viral potential against isolate of SARS-CoV-2 with IC50 values of 8.439 μM with significant improvement (p < 0.001). In addition, the complex showed IC50 in vitro 3CL-protease inhibition with IC50 7.216 µM. Molecular docking has revealed that formula components have good predicted pocket accommodation of the SARS-CoV-2 3-CL protease. An optimized formulation of SIT-MEL could guarantee both enhanced delivery to the target cells and the enhanced cellular uptake with promising activities against SARS-CoV-2.
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