Recently, some attempts have been made to construct new families of models to extend well-known distributions and at the same time provide great flexibility in modeling data in practice. So, several classes by adding shape parameters to generate new models have been explored in the statistical literature. We propose a new generalization of the three-parameter extended Weibull distribution pioneered by Pappas et al. (2012) by using the generator by Marshall and Olkin (1997). The new model is called the (P-A-L) extended Weibull, where (P-A-L) denote the first letters of the scientists Pappas, Adamidis and Loukas.
Background: In the peri-and postmenopausal years, abnormal uterine bleeding (AUB) is the most prevalent reason for gynecological appointments.
Aim of the work:To see how office hysteroscopy and three-dimensional (3D) ultrasonographic measurements of endometrial volume affected endometrial volume and if those methods could predict malignant conditions and hyperplasia of the endometrium and if they could exclude serious intrauterine pathology in perimenopausal women with irregular uterine bleeding to minimize further operative interventions, especially for surgically high-risk patients or not?. Patients and methods: This study was conducted at Al Azhar University in Al Hussein university hospital from March 2017 to October 2019 Obstetrics and Gynecology department. The research included 100 studied cases complaining of perimenopausal bleeding at the outpatient clinic. Results: hyperplasia followed by complex endometrial hyperplasia and only 1 case of endometrial carcinoma was discovered. In group 2 most common endometrial histopathology was discovered proliferative endometrium then secretory endometrium and 6 cases of atrophic endometrium.
Conclusion:In cases of perimenopausal bleeding, this study demonstrated the diagnostic value of office hysteroscopy and threedimensional (3D) ultrasonographic endometrial volume measurement, and showed that combining those 2 modalities of diagnosis had led to increase the ability & sensitivity of diagnosis and With perimenopausal women with irregular uterine bleeding, the capacity to rule out significant intrauterine disease to minimize further operative interventions, especially for surgically high-risk patients.
There are some technical and environmental issues associated with the usage of ordinary Portland cement (OPC) in well cementing. These concerns persuaded the researchers to search for alternative materials to overcome the technical challenges and to provide eco-friendly cement systems. The use of geopolymer technology is widespread across many industries, particularly the construction sector. Oil and gas well cementing hasn't yet seen a full-scale deployment of it, though. This work evaluates the possibility of using hematite to develop a heavy weight geopolymer system for cementing operations. The biggest challenge in this work was developing a flowable heavy weight geopolymer formulation with good rheological properties and sufficient thickening time. The evaluation included rheological properties, fluid filtrate, strength, petrophysical and dynamic elastic properties for the developed class F fly ash (FFA) hematite-based geopolymer formulation. The results showed that the developed high density geopolymer system possessed acceptable properties making it a possible candidate for different cementing applications.
Background: Primary premature ejaculation (PE) can be effectively treated with sildenafil citrate, according to recent research. This study evaluated sildenafil citrate efficacy in primary PE treatment, considering the female perspective. Methods: Sixty sexually active men diagnosed with primary PE were split into two groups randomly and followed for 6 months. Group A received 50 mg of sildenafil citrate one hour before sexual activity in accordance with standard dosing guidelines (not fewer than once a week), while Group B received paroxetine 20 mg daily for six months. At baseline, 3 months, and 6 months following therapy, the intravaginal ejaculatory latency time (IELT), PE grade, intercourse satisfying score (ISS), intercourse frequency, and drug-associated side effects were noted. Results: Both groups showed significant improvements in all measurements following 3 or 6 months of therapy, with no critical changes between two time points. However, sildenafil citrate was found to be significantly more effective than paroxetine in improving all parameters at both 3 and 6 months (P = 0.001). Conclusion: Sildenafil citrate is a highly beneficial treatment for primary PE and is more effective than paroxetine.
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