Scientific evidence is mounting that synthetic chemicals used as food additives may have harmful impacts on health. Food additives are chemicals that are added to food to keep it from spoiling, as well as to improve its colour and taste. Some are linked to negative health impacts, while others are healthy and can be ingested with little danger. According to several studies, health issues such as asthma, attention deficit hyperactivity disorder (ADHD), heart difficulties, cancer, obesity, and others are caused by harmful additives and preservatives. Some food additives may interfere with hormones and influences growth and development. It is one of the reasons why so many children are overweight. Children are more likely than adults to be exposed to these types of dietary intakes. Several food additives are used by women during pregnancy and breast feeding that are not fully safe. We must take specific precaution to avoid consuming dangerous compounds before they begin to wreak havoc on our health. This study is intended to understand how the preservatives induce different health problem in the body once it is consumed. This review focuses on some specific food additives such as sodium benzoate, aspartame, tartrazine, carrageenan, and potassium benzoate, as well as vitamin A. Long-term use of food treated with the above-mentioned food preservatives resulted in teratogenicity and other allergens, according to the study. Other health issues can be avoided in the future by using natural food additives derived from plants and other natural sources.

Hydrogen has universally been considered a reliable source of future clean energy. Its energy conversion, processing, transportation, and storage are techno-economically promising for sustainable energy. This study attempts to maximize the production of H2 energy using nanocatalysts from waste aluminum chips, an abundant metal that is considered a potential storage tank of H2 energy with high energy density. The present study indicates that the use of waste aluminum chips in the production of H2 gas will be free of cost since the reaction by-product, Al2O3, is denser and can be sold at a higher price than the raw materials, which makes the production cost more efficient and feasible. The current framework investigates seven different copper oxide-based graphene nanocomposites that are synthesized by utilizing green methods and that are well-characterized in terms of their structural, morphological, and surface properties. Reduced graphene oxide (rGO) and multi-layer graphene (MLG) are used as graphene substrates for CuO and Cu2O NPs, respectively. These graphene materials exhibited extraordinary catalytic activity, while their copper oxide composites exhibited a complete reaction with feasible techno-economic production. The results revealed that the H2 production yield and rates increased twofold with the use of these nanocatalysts. The present study recommends the optimum reactor design considerations and reaction parameters that minimize water vaporization in the reaction and suggests practical solutions to quantify and separate it. Furthermore, the present study affords an economic feasibility approach to producing H2 gas that is competitive and efficient. The cost of producing 1 kg of H2 gas from waste aluminum chips is USD 6.70, which is both economically feasible and technically applicable. The unit cost of H2 gas can be steeply reduced by building large-scale plants offering mass production. Finally, the predicted approach is applicable in large, medium, and small cities that can collect industrial waste aluminum in bulk to generate large-scale energy units.

The chlorinated tetracyclic 1,5-dichloro-9,10-dihydro-9,10-ethanoanthracen-12-yl)-N-methylmethanamine 1, a maprotiline analog, has been synthesized via reduction and the Diels–Alder reaction followed by reductive amination of aldehyde 2.1D-NMR (DEPT) and 2D-NMR (HSQC, DQF-COSY) techniques were recruited for structural elucidation in addition to HRMS. Density functional theory calculations were performed to identify the possible isomers of the intermediate compound aldehyde 2; these calculations were in good agreement with experimental results where aldehyde 2 could exist in three isomers with comparable energies. In addition, the side chain of this aldehyde 2 was extended via the Wittig reaction to obtain the unsaturated ester 5 that was subjected to selective olefinic catalytic hydrogenation to obtain the corresponding saturated ester 6. Molecular docking simulation showed that all the compounds (1, 2, 5, and 6) have high antidepressant activities and form stable complexes with LeuT by inhibiting the neurotransmitter reuptake at the synapse and hence are good candidates as antidepressant drugs.