In this paper , number of heterocyclic compound with five and six membered, Such as substituted imidazole, triazin and thiazolidine. The compound N-(1,3benzothiazol-2-yl)-2-chloro acetamide was prepared from the reaction of the 2-amino benzothiazole with chloroacetyl chloride. The product N-(1,3-benzothiazol-2-yl)-2chloro acetamide was reacted with thiourea and urea to prepare both 4-(1.3benzothiazol-2-yl amino)-1,5-dihydro-2H-imidazole-2-thione and 4-(1,3benzothiazol-2-yl amino)-1,5-dihydro-2H-imidazol-2-one, respectively. As did compound N-(1,3-benzothiazol-2-yl)-2-chloro acetamide with thiosemicarbazide and semicarbazide to prepared the two compounds 5-(1,3-benzothiazol-2-yl amino)-1,6-dihydro-1,2,4-triazine-3(2H)-thione and 5-(1,3-benzothiazol-2-yl amino)-1,6dihydro-1,2,4-triazine-3(2H)-one, respectively. Also compound N-(1,3-benzothiazol-2-yl)-2-chloro acetamide with ammonium thiocyanate to prepare the compound 3-(1,3-benzothiazol-2-yl amino) thiazolidin-4-one. From the reaction of compound N-(1,3-benzothiazol-2-yl)-2-chloro acetamide with phenyl thiourea attended 4-(1,3benzothiazol-2-yl amino)-1-phenyl-1,5-dihydro-2H-imidazole-2-thio. Also from the reaction of 2-amino benzothiazole with phthalic anhydride or malic anhydride attended compounds2-(1,3-benzothiazol-2-yl carbonyl) benzoic acid and 4-(1,3benzothiazol-2-yl amino)-4-oxobut-2-enoic acid and 2-(1H-benzoimidazol-2-yl)-N-(1,3-benzothiazol-2-yl) benzamide and 3-(1Hbenzoimidazol-2-yl)-N-(1,3-benzothiazol-2-yl) acrylamide, respectively. And by reaction compound 2-(1,3-benzothiazol-2-yl carbonyl) benzoic acid and 4-(1,3benzothiazol-2-yl amino)-4-oxobut-2-enoic acid or 2-(1H-benzoimidazol-2-yl)-N-(1,3-benzothiazol-2-yl) benzamide and 3-(1H-benzoimidazol-2-yl)-N-(1,3benzothiazol-2-yl) acrylamide with o-phenylene diamine attended compounds 2-(1H-benzoimidazol-2-yl)-N-(1,3-benzothiazol-2-yl) benzamide and 3-(1Hbenzoimidazol-2-yl)-N-(1,3-benzothiazol-2-yl) acrylamide, respectively. The synthesized compounds are identified by physical melting points, color change and spectroscopic methods such as IR, proton-NMR.

This study involved synthesize (1,3) oxazepine. The step 1 includes the preparation of compound (1), (5-Bromo-2-mercapto-6-(4-methoxyphenyl) pyrimidin-4(3H)-one), by the condensation of anisaldehyde and ethylbromoacetat and thiourea in EtOH. In the step2, chalcones (2-6) have been produced. The reaction of compound (1) with chalcones (2-6) that gives azo Michael adduct (7-11) is made in the third step. Schiff's bases (12-16) were prepared by the reaction ketones (7-11) with 2,4dinitroaniline. Finally preparation of new benzo [1,3] oxazepine compounds (17-21) are prepared by the reaction of phthalic anhydride with Schiff's bases. The synthesized compounds are identified by physical (melting points, colour change) and spectral methods such as (IR, proton-nmr).