INTRODUCTION Although Titanium has high mechanical properties, the lack of its biological activity led to the need for its surface modification. Titanium surface coating is one of the additive surface modifications. Adding new materials to titanium surface can bring new properties to it yet maintaining its original properties. In this study, 70S30C bioglass was used to coat the Titanium substrate by using the electrophoretic deposition technique (EPD). OBJECTIVE Optimizing EPD parameter (voltage amount) for 70S30C bioglass nanoparticles coating on Titanium substrate. The aim of the current study is to evaluate the effect of the voltage amount on the produced coating thickness. METHODS Twenty-four Titanium discs were prepared (10x1.5 mm), sandblasted, and ultrasonically cleaned in ethanol. Bioglass 70S30C was prepared by sol-gel technique followed by ball milling to produce nanoparticle powder. Characterization of the powder was done by transmission and scanning electron microscope. Titanium discs were divided into three groups (G1, G2, and G3) (n=8) each. They were subjected to EPD coating with 10, 30, and 50 Voltage, respectively. The coating thickness was then assessed by SEM images of the cross-section of the used specimens. RESULTS TEM images revealed a highly agglomerated nano-powder with a size range of 8-20 nm. The coating thickness was increased by increasing the voltage amount under the same deposition time. CONCLUSION EPD proved to be a versatile and innovative coating technique with a low cost. The resultant coat thickness is directly proportional to the voltage amount.

INTRODUCTION: Titanium implants are used vastly in dentistry owing to their durability, biocompatibility and mechanical strength making them convenient for high mechanical load implementations. However, titanium surfaces are not bioactive and do not provide effectual bonding with the host bone resulting in loosening and subsequent failure at the bone-implant interface. The coatings of bioactive glass (BG) are used to alter the implant surface chemistry to boost cell functions that promote better osseointegration. OBJECTIVES: This study aimed to evaluate the antibacterial activity of BG nanoparticles coating deposited to modify titanium surface to enhance osseointegration. Methodology: Twenty-four titanium-alloy (Ti-6Al-4V) substrates were sandblasted, ultrasonically cleaned and divided into 4 equal groups (A, B, C and D). A and B were the control groups while C and D were coated with 70 mol% silica oxide -30 mol% calcium oxide (70S30Ca) BG nanoparticles using electrophoretic deposition technique (EPD). The BG was prepared by modified sol-gel technique then milled into nanoparticles. The antibacterial action of the obtained coatings against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) bacteria was characterized 24 h following incubation at 35°C using well diffusion susceptibility test. RESULTS: After incubation, both control and test specimens were showing normal bacterial growth with no observed inhibition zones for both types of bacteria. CONCLUSIONS:The deposited 70S30Ca BG coating on titanium-alloy substrates using EPD was showing no antibacterial effect against S. aureus and E. coli.