patients are received traditional method. In the HFNC group, the changes of P/F ratio and HR is significantly greater compared to the traditional group (P/F ratio: 285 (74.4) to 311.2 (112.0) vs 323.1 (98.2) to 236.2 (79.8); p=0.027, ABP (m): 84.0 (12.3) to 89.4 (11.9) vs 83.6 (14.5) to 84.5 (12.9) mmHg; p=0.007). However, HR and RR were not different between the groups. By using HFNC, mean P/F ratio of post extubation was as same as pre extubation. Furthermore, there was no difference in re-intubation rate (14.8% vs 7.8%). Conclusions: Early HFNC before extubation may prevent hypoxemia after extubation. When using HFNC starting from just before extubation, we can have predictable oxygenation after extubation.
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