SUMMARYBackground: A food borne illness was reported in GaEast district of Greater Accra Region among school children in May, 2007 after eating food provided at school. The objective of the investigation was to determine the source, mode of contamination and the causative agent. Methods: A case-control study was conducted, cases were schoolchildren with abdominal symptoms and controls were children of the same sex and class without any symptom during the same period. The school children were selected by systematic sampling. Food handlers and the children were interviewed by a structured questionnaire. Food handlers were physically examined and their stools and blood examined. The kitchen for food preparation was inspected. Risks of food borne infection from the foods eaten were determined using attack rates . Results: The minimum, peak and maximum incubation periods were 2, 11 and 61 hours respectively. The source was rice and groundnut soup (with the highest attack rate difference). Stool and blood samples of food handlers were not infective. Storage facility for food items was poor. No food samples were available for organism isolation. A protocol to prevent such outbreaks was nonexistent. Conclusion: The short incubation period and symptoms presented suggest an infective origin. The storage of the meat may potentially have been the point of contamination. The study showed that the schoolchildren ate contaminated food although the investigation could not determine the causative agent. Protocols to prevent such outbreaks need to be developed for the schools.
Study objective-To evaluate the completeness of notification of deaths by the National Health Service Central Register (NHSCR) for England and Wales. Design-Deaths for a birth cohort were ascertained through scanning the relevant volumes of NHSCR. Attempts were made to confirm these deaths and additional deaths were ascertained through searching local records. Logistic regression was used to investigate how the probability of a death being missed by NHSCR varied with the year of birth, age at death, sex, and social class.
Background . Few studies have focused on the effects of COVID-19 on African populations. During the first epidemic wave in Senegal (May 1 to July 31, 2020), COVID-19 cases were isolated in treatment centers of epidemics (TCEs). We described the demographics and outcomes of COVID-19 cases in TCEs. Patients and Methods . All cases with laboratory-confirmed COVID-19 in Thiès medical region of Senegal were included. Results . COVID-19 was confirmed in 600 cases. Median age of cases (men: 357, 59.5%; women: 243, 40.5%) was 34.0 years. The incidence was 12 per 100,000 inhabitants per month. Overall, 46 (7.7%) cases had a severe or critical form of the disease, and nine of them died. Of 455 cases quarantined in non-hospital TCEs, 340 (74.7%) had no symptom and 115 (25.3%) had mild or moderate symptoms. Conclusion . In this African retrospective cohort, COVID-19 cases were young and mostly asymptomatic with a low case fatality rate.
Introduction: HIV resistance to antiretroviral is currently a global concern, and requires increased surveillance in a context of widespread ARV treatment. Objective: To evaluate early warning indicators of HIV resistance to ARVs in the Hospital of Tivaouane (Senegal) where viral load was not routinely available. Methods: This is a cross-sectional retrospective study from 2008-2016. The extraction tool (May 2010 version) was used to analyze the EWI. Results: We collected 360 HIV positive patients followed on average for 3.57 years ± 3.02. 2009, 2010 and 2012 recorded 100% ARV prescribing rates. Throughout the study period, the percentage of patients lost to follow-up during the first 12 months of treatment was less than 20%. Virtually, all patients were still under primary ARVT over 12-month treatment. All patients (100%) withdrew their ARV drugs on time. No stock storage regarding various classes of ARVs was noted during the study period. Conclusion: At the end of this study we recommend to maintain regular follow-up of EWI, and combine it with the achievement of viral load.
Background: Clinical manifestations of scabies in children differ from those of adults: difference accentuated by the presence of certain contributing factors which contributes to delayed diagnosis and management. The objective of our study was to study the epidemiological, clinical, therapeutic and evolutionary aspects of scabies in children. Materials and Methods: From January 1st, 2012 to December 31st, 2017, a descriptive retrospective study was conducted in the dermatology department of the Regional Hospital Center of Thiès. The study included records of children aged 0 to 15 years in outpatient care. The data was entered and analyzed using a computer with Epi info7 software version 3.5.4. Results: Of the 19129 patients seen in consultation, 2284 were children, of whom 69 had scabies, with a hospital prevalence of 0.36%. The average age was 4.64 years and the sex ratio were 1.46. Out-of-school children predominated with 47.8%. Mothers were out of school in 79.71%. Voluntary cosmetic depigmentation was practiced by 65.22% of mothers. The average consultation time was 21.86 days, pruritus was present in 56.5% of cases. Topography with interdigital spaces predominated in 81.15% of cases. All the children had been treated with benzyl benzoate. The cure rate was 92.7%. The complications were bacterial superinfection in 60.87% of cases, eczema in 4.34% and acute glomerulonephritis in 1.44% of cases. Conclusion: Scabies of the child is still relevant. Its prevalence and complications make it a real health problem and can be life-threatening in children. The main objective remains prevention.Scabies of the child: Epidemiological, clinical, Scabies of the child: Epidemiological, clinical, therapeutic and evolutionary aspects in the service therapeutic and evolutionary aspects in the service of Dermatology of the Regional Hospital of Th iès of Dermatology of the Regional Hospital of Th iès (Senegal): (Senegal): About 69 cases (
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