BackgroundPoststreptococcal syndrome (PSS) can be a consequence of nonpurulent primary infection with group A streptococci (GAS). Postreptococcal uveitis is a well recognized entity with quite a few descriptions in the literature, but so far no conjunctival involvement has been reported.The aim of the study is to present a rare case of postreptococcal conjunctival lesions mimicking a lymphoma.Case presentation19-years-old Caucasian female presented with pink, nodular infiltrates in the right conjunctiva that occurred a few months after upper respiratory tract infection and tonsillectomy. Histopathological examination of collected lesion samples revealed inflammatory reaction with lymphocytes proliferation and failed to rule out a myeloma. Complementary flow-cytometry did not show monoclonal proliferation of lymphocytes B. During follow-up we observed the complete regression of conjunctival lesions after the benzyl penicillin treatment prescribed by ENT specialist due to elevated plasma ASO levels. Therefore, we suppose that those lesions must have represented a part of poststreptococcal syndrome.ConclusionsTo conclude, this is, to the best of our knowledge, the first report of conjunctival involvement in the course of PSS related to group A streptococci.

The aim of this paper is to present the case of a child with reactive lymphoid hyperplasia of the conjunctiva, whose lesion regressed completely after oral glucocorticosteroid treatment. The final diagnosis was established on the basis of a histopathological examination combined with an immunohistochemical staining test and the exclusion of other conditions that could generate similar lesions. Because of the lack of general contraindications, methylprednisolone treatment was administered and local improvement was obtained. Reactive lymphoid hyperplasia of the conjunctiva is rarely found in children. It is important to emphasize the fact that lymphoproliferative lesions in the conjunctiva may, on the one hand, represent a lymphoma; on the other hand, they may be caused by a benign lesion-reactive lymphoid hyperplasia of the conjunctiva. Many treatment methods have been reported in the literature on the subject, but there are no clear guidelines concerning therapy in children.

Uveal melanoma is the most common primary malignancy of the eye in adults. It may involve the choroid and ciliary body, and in only 2-3% of cases it involves the iris. We present a case of a 56-year-old patient with a 6-year history of unilateral, inflammatory, refractory glaucoma of the right eye. Due to acquired heterochromia and heterogeneous thickness of the iris, iris melanoma was suspected, but the incisional biopsy did not confirm the diagnosis. In the next months, the lesion enlarged and the eye globe was enucleated. Histopathological examination revealed an iridociliary melanoma with annular growth pattern.

The purpose of this study was to perform an ophthalmological assessment in children with intracranial cysts and to assess the correlation between the occurrence of cysts and visual disorders. The documentation of 46 children with intracranial cysts, monitored by the Children’s Outpatient Ophthalmology Clinic, Poznan, Poland was analysed. The best corrected visual acuity (BCVA), the alignment of the eyes, visual evoked potentials (VEP), comprehensive eye examination were performed in all patients. Additional ophthalmological tests were conducted to eliminate other causes of decreased visual acuity.Included in the final analysis were 26 children (52 eyes). The average age at the last visit was 10.3 years. Sixteen children (61.5%) had arachnoid cysts located in the posterior cranial fossa, 3 children (11.5%) in the middle cranial fossa, while 7 children (27%) had a pineal cyst. Decreased BCVA was found in 13 children, abnormal VEP in 13, strabismus in 14 patients (53.9%), nystagmus in 5 patients (19.2%), and double vision in 2 patients (7.7%). Numerous visual disorders in children with intracranial cysts suggest the necessity to carry out enhanced ophthalmological diagnostics in these patients. In the examined patient group, visual disorders occurred mostly in the case of arachnoid cysts of the posterior fossa.

Introduction Carotid arthrosclerosis can be a cause of visual impairment. It has been observed that carotid endarterectomy has a positive effect on ophthalmic parameters. The aim of this study was to evaluate the impact of endarterectomy on the optic nerve function. Materials and methods 54 asymptomatic patients (19 women and 35 men - 108 eyes) with unilateral carotid stenosis >70% of internal carotid artery, were recruited to the study. All of them were qualified for the endarterectomy procedure. The whole study group underwent Doppler ultrasonography of internal carotid arteries and ophthalmic examination before the surgery, with 22 of them (11 women and 11 men) were examined after the endarterectomy. The ophthalmic examination included; distant best-corrected visual acuity, measurement of the intraocular pressure, electrophysiology (pattern visual evoked potentials), perimetry, and optical coherent tomography (the retinal nerve fiber layer thickness). Discussion Carotid arteries supply brain and face with blood. Extensive research has observed a concomitant improvement in eyesight after enduring carotid endarterectomy in patients with artery stenosis. This effect was associated with a better blood flow in the ophthalmic artery and its branches, the central retinal artery and the ciliary artery; the major blood supply of the eye. Results The present study proved that carotid endarterectomy has a positive impact on the function of the optic nerve. The visual field parameters and amplitude of pattern visual evoked potentials significantly improved. Preoperative and postoperative values of intraocular pressure and the retinal nerve fiber layer thickness remained stable.

This article aims to present up-to-date information on ocular symptoms of pediatric multi-system inflammatory syndrome. The reviewers obtained the results based on a search of an electronic database. The pediatric multi-system inflammatory syndrome appears a few weeks after COVID-19 in children. The exact etiology remains unclear. It is diagnosed based on clinical and laboratory criteria. The most prevalent manifestation of the syndrome is non-purulent conjunctivitis (observed in around 50% of cases). The other ocular findings in the pediatric multi-system inflammatory syndrome can be; eyelid swelling, bilateral uveitis or vitreous hyperreflective dots in the posterior vitreous. The treatment of the ophthalmic symptoms is systemic and topical, targeting the enhanced inflammatory response of the organism and the presence of the given ocular findings.

Introduction: Dry eye disease (DED) can be caused by many factors and conditions. It is a multifactorial disease, in which ocular surface inflammation plays an important role in the pathogenesis. Aim of the study:To assess efficacy of pranoprofen ophthalmic solution 0.1% applied for treatment of non-infectious conjunctivitis in patients with symptoms of dry eye disease. Material and methods: Prospective, single-arm, open, noninterventional study. Near and distant best corrected visual acuity, intraocular pressure measurement with air-puff tonometer as well as Schirmer I test, bulbar hyperemia, conjunctival edema, tear break-up time (TBUT), cornea and conjunctival staining score and lid-parallel conjunctival folds (LIPCOF) were assessed. Slit lamp examination included anterior segment and fundus examination. Patients were treated with pranoprofen ophthalmic solution 0.1% 4 times a day for 2-4 weeks.Results: 13 patients were screened, and 12 fulfilled inclusion criteria. The most significant improvement was observed in the change of subjective dry eye symptoms reported by the patients (equal for all OSDI sections). Improvement was observed in conjunctival hyperemia as well as degree of conjunctival and corneal staining (Oxford scale). There was no change in TBUT and LIPCOF. There were two non-serious adverse events reported during the course of the study. Conclusions: Pranoprofen ophthalmic solution 0.1% is an effective and safe treatment for non-infectious conjunctivitis with mild to moderate dry eye symptoms. Add-on treatment with pranoprofen ophthalmic solution 0.1% greatly improved the patient's subjective symptoms (OSDI score).

Carotid arteriosclerosis is the main cause of the stroke but it can also lead to ophthalmic symptoms. In this article, we aim to present four patients. All of them had hemodynamically significant but asymptomatic unilateral carotid stenosis and underwent internal carotid endarterectomy. Postoperatively, their visual function improved. Mean deviation in perimetry and values of amplitudes in pattern visual evoked potentials increased. Two patients improved visual acuity; in the other two, it remained stable.