Objective: This study is the first to analyse the prevalence of oral candidiasis in oncohaematological patients by physical and oral cytopathological examinations.Methods: This is a cross-sectional and observational study with a retrospective sample composed of participants hospitalised in the haematology clinic, who were diagnosed with haematological diseases. All participants received an oral mucosal examination and scraping from oral mucosa.Results: Of the 62 participants, 56.5% were male and 82.3% were white, with mean age of 57 years. Lymphoma was the most common haematological disease (24.2%). In total, 48.4% of the sample was diagnosed with oral candidiasis. Of the participants with oral candidiasis, 13 (21.0%) had a clinical diagnosis. Cytopathological analysis revealed 17 more (27.4%) cases without oral lesions indicative of candidiasis. Erythematous candidiasis (P = 0.02), pseudomembranous candidiasis (P < 0.001), clinical candidiasis (P < 0.001), fibrous hyperplasia (P = 0.032), and coated tongue (P = 0.012) showed a correlation with a candidiasis cytopathological diagnosis.
Conclusions:Oral candidiasis is common among patients with haematological disease, and the cytopathological examination proved to be a useful tool, confirming clinical diagnosis of candidiasis and identifying subclinical cases. These data are of great relevance considering the possible complications that these patients may develop, such as longer hospitalisations, worsening of the general condition or even death due to candidemia.
Primeira submissão em 14/03/07 Última submissão em 14/02/08 Aceito para publicação em 15/02/08 Publicado em 20/02/08 Contribuição da citopatologia para o diagnóstico de carcinoma de células escamosas oral Contribution of cytopathology to the diagnosis of oral squamous cells carcinoma
relato de caso case report Primeira submissão em 31/11/06 Última submissão em 04/10/07 Aceito para publicação em 11/10/07 Publicado em 20/12/07 Coexistência de pênfigo vulgar e infecção pelo vírus herpes simples na mucosa oral Coexistence of pemphigus vulgaris and herpes simplex virus infection in oral mucosa
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