Superficial fungal infections of the hair, skin and nails are a major cause of
morbidity in the world. Choosing the right treatment is not always simple because of
the possibility of drug interactions and side effects. The first part of the article
discusses the main treatments for superficial mycoses - keratophytoses,
dermatophytosis, candidiasis, with a practical approach to the most commonly-used
topical and systemic drugs , referring also to their dosage and duration of use.
Promising new, antifungal therapeutic alternatives are also highlighted, as well as
available options on the Brazilian and world markets.
Superficial fungal infections of the hair, skin and nails are a major cause of
morbidity in the world. Choosing the right treatment is not always simple because of
the possibility of drug interactions and side effects. The first part of the article
discusses the main treatments for superficial mycoses - keratophytoses,
dermatophytosis, candidiasis, with a practical approach to the most commonly-used
topical and systemic drugs , referring also to their dosage and duration of use.
Promising new, antifungal therapeutic alternatives are also highlighted, as well as
available options on the Brazilian and world markets.
Stiff skin syndrome is a rare scleroderma-like disorder of unknown etiology characterized by stone-hard indurations of skin, mild hypertrichosis and limited joint mobility. No effective treatment has yet been found. Exercises and rehabilitative therapy are important in maintaining the patient's quality of life. The authors present a case of a two-year-old boy with progressive skin hardening since he was eightmonth old and secondary restricted joint mobility, diagnosed as Stiff skin syndrome. Keywords: Contracture; Fascia; Mucopolysaccharidoses; Rare diseases; Scleroderma, systemic Resumo: Síndrome stiff skin é doença rara, esclerodermiforme, de etiologia desconhecida, caracterizada por endurecimento pétreo da pele, hipertricose leve e limitação da mobilidade articular. Não há tratamento efetivo até o momento. Exercícios e reabilitação são importantes para manter a qualidade de vida do paciente. Os autores apresentam caso de um menino de dois anos de idade com endurecimento cutâneo progressivo desde os oito meses de idade e restrição secundária da mobilidade articular, diagnosticado como Síndrome stiff skin.
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