ONTRAST NEPHROPATHY IS A recognized complication after coronary angiography and intervention that has been associated with prolonged hospitalization and adverse clinical outcomes. 1-3 It is reported that 14.5% of patients develop a 25% increase in serum creatinine levels following cardiac catheterization. 2 This problem assumes greater and greater importance with increased use of invasive radiological procedures to diagnose and treat coronary artery disease. Contrast nephropathy is potentially preventable because the administration of radiocontrast agent is predictable and high-risk populations also have been identified. 4 Patients at greatest risk are those with impaired renal function, 5 particularly that caused by diabetic nephropathy. 6 However, other than the use of intravenous hydration 2 and lowosmolality contrast media, 7 no previ-Author Affiliations:

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