Introduction: an oro-antral communication is defined as a permanent pathological connection between the maxillary sinus and the septic oral cavity. Several flaps can be used for the closure (buccal flap, palatal flap, combination techniques) but relapses occur often in case of a large defects and underlying general conditions. Bichat fad pad flap is a multipotent pedicled fatty tissue that is easily accessible from the oral cavity that can be used for the closure of medium-sized defects, even in immunocompromised patients due to its stem cell capacity. Materials and methods: the medical information of the patients diagnosed with oro-antral communications who were admitted and treated in the Oral and Maxillo-Facial Clinic Targu Mures, between 2013 and 2020 were analyzed. A database containing general information, reported causes, associated diseases, surgical methods used during admission, and relapses, was created. The information was statistically processed. The written consent and ethical approval were obtained. Results: the study shows that from a total of 140 cases, 72 were treated using buccal advancement flap, 49 using Bichat fat pad flap, and 19 using palatal flaps. The dimensions of the communications ranged between 0.3 cm and 1.5 cm. Several statistically significant results could be found when comparing the surgical methods. Of the 72 patients treated with buccal advancement flaps, 25 presented relapses as opposed to the patients treated with Bichat fat pad flaps who showed no complications, p < 0.05. Analysing this aspect further, all large defects (10 cases) ranging from 0.6 cm to 1.5 cm treated with advancement buccal flaps (Rehrmann flaps) showed relapses (p < 0.05). Considering the general conditions, out of 7 patients who received radiotherapy 4 presented relapses, as opposed to the healthy patients, p < 0.05. Regarding the reintervention for the relapsed cases, the majority of the cases treated a second time with buccal advancement flap (5 out of 7 cases) failed as opposed to the Bichat fat pad flap with no further relapses (p < 0.05). Conclusions: the most frequently used surgical treatment is the buccal flap, which also has the highest relapse rate. Both primary treatment with Bichat fat-pad flap and re-treatment of relapses using this flap have had 100% success rates, even in patients with general associated conditions, in contrast with patients treated by using the buccal flap. The dimensions of the oro-antral communication and general conditions are crucial factors for the success of the surgical treatment.
Spruce is a used material in the wood industry and bark is regarded as a by-product. The aim of this study was to provide information about natural bioactive compounds from spruce (Picea abies L.) bark with potential therapeutic applications such as antibacterial activity against human pathogens. Spruce bark extract was obtained by the conventional aqueous extraction (EAM), and second with ultrasounds (USM). It was determined the total polyphenols by spectrophotometric methods and individual polyphenols by high-performance liquid chromatography (HPLC). For the determination of minimum inhibitory concentration was used microdilution technique. The following strains were tested: Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The yield of extracted polyphenols in the case of spruce bark extract was of 33.8mg gallic acid/gfor EAM and 28.73 mg gallic acid/g for USM. The compounds identified in samples, by HPLC, were vanillic acid and taxifolin.It was found that both extracts have antibacterial capacity for all bacteria tested. The antibacterial effect of both extracts was stronger against Gram positive cocci compared with Gram negative bacilli.Antimicrobial spectra and activities of the fractions and pure isolated compounds from the spruce bark, can be suggested the use of spruce bark in pharmaceutical preparations and as well as a food preservative.
Oral malodour is the general term used to describe disagreeable odor in expired air with psychological component in patients with special needs. The aim of this study is to evaluate the effect of essential oil mouthwash on oral halitosis and periodontal status of patient with special needs. 26 patients aged between 16-45 were enrolled in this single-blind, parallel-group study. Informed consent was obtained. The following parameters were recorded: gingival index, plaque index, organoleptic breath assessment, and BANA test from tongue coating samples prior to treatment with essential oil mouthwash (group 1) or a placebo (group 2) at baseline and 28 days after the start of treatment. There were significant differences (p[0.05) in plaque and gingival index after treatment with essential oil mouthwash compared to the placebo. The results provide a statistically significantly greater level of efficacy in controlling established plaque and gingival index after use of essential oil mouthwash. Therefore, it can be recommended in halitosis therapy in order to maintain a good periodontal status.
Halitosis is an embarrassing symptom with a significant social impact. Periodontal disease, tongue coating, interdental food impaction, and dental cavities are the predominant causative factors. The aim of this study is to evaluate the effect of essential oil mouthwash on halitosis. 30 patients aged between 16-25 were enrolled in this single-blind, parallel-group study. Informed consent was obtained. The following parameters were recorded: gingival index, plaque index, organoleptic breath assessment, and BANA test from tongue coating samples prior to treatment with essential oil mouthwash (group 1) or a placebo (group 2) at baseline and 28 days after the start of treatment. Histological examinations were performed from gingival tissue. There were significant differences (p[0.05) in plaque and gingival index after treatment with essential oil mouthwash compared to the placebo. The results provide a statistically significantly greater level of efficacy in controlling established plaque and gingival index after use of essential oil mouthwash. Therefore, it can be recommended in halitosis therapy.
Obesity is a complex and multifactorial disease. Its relationship with periodontal disease and other chronic diseases is well documented but the underlying mechanism is under investigation. It is quite difficult to say whether obesity predisposes an individual to periodontal disease or periodontal disease affects lipid metabolism, or both. The purpose of the study consists in evaluating the periodontal clinical parameters in obese patients diagnosed with chronic periodontitis, before and after surgical treatment of obesity through the procedure called gastric sleeve Our study consists of a group of 38 patients diagnosed with morbid obesity who were surgically treated by gastric sleeve surgery at the Surgery Department II of the County Emergency Clinical Hospital Targu Mures. Patients with pre-operative and psot-operative examination at 3 months and 6 months respectively in which either periodontal index were index of plaque, index of probing depth and index of bleeding on probing. Correlations between parondontal clinical indexes (PD, PI, BOP) were calculated before and after gastric sleeve at 3 and 6 months respectively. The bleeding on probing index (BOP) reveals a complete decrease in postoperative bleeding time. Patients at 3 months experience minor bleeding during testing and no longer showing bleeding at 6 months. The results provide evidence that there is a link between obesity and periodontitis, however the risk factors that aggravate these diseases should be clarified to elucidate the direction of this association.
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