Rainfall and temperature are climatic variables mostly affected by global warming. This study aimed to investigate the temporal trend analysis in annual temperature and rainfall in the Southern Togo for the 1970-2014 period. Daily and annual rainfall and temperature were collected from four weather stations at Atakpame, Kouma-Konda, Lome, and Tabligbo. The temperature variability was determined by the Standardized Anomaly Index (SAI) and the annual rainfall variability was determined using the Standardized Precipitation Index (SPI). The Mann-Kendall test was used for trend analysis. Mann-Kendall statistical test for the mean annual, mean annual minimum and maximum temperature from 1970 to 2014 showed significant warming trends for all stations except Kouma-Konda where mean annual maximum temperature had exhibited non significant cooling trend (P = 0.01). For Standardized Precipitation Index in the 12-month time scale, dry tendency dominates Atakpamé (55.7%) and Kouma-Konda (55.5%) while wet tendency dominates slightly Lomé (50.9%) and Tabligbo (51.4%). The Mann-Kendall test revealed an increasing trend in standardized anomaly index at all the sites, prejudicial to rainfed agriculture practiced by about 90% of Togolese crop growers. The trend analysis in the climate variables indicated a change in climate that necessitates some specific actions for resources management sustainability and conservation.