A series of some transition metal, Fe(III), Cu(II), Cd(II), and Hg(II), complexes with N′,2‐bis((Z)‐2‐oxoindolin‐3‐ylidene)hydrazine‐1 carbohydrazide (H3L) ligand have been synthesized, and their structures were elucidated based on their spectral analyses (Fourier transform infrared [FT‐IR], 1H nuclear magnetic resonance (NMR) and 13C NMR, UV‐visible (UV‐Vis), electron spin resonance (ESR), powder X‐ray diffraction [XRD], and mass spectroscopy), elemental analyses, conductance, and magnetic susceptibility measurements. The structures of the H3L ligand and its metal complexes were optimized using the DMol3 tool in the material studio package. The ligand behaves as binegative N2O3 pentadentate in [Fe(HL)(Cl)]·2H2O complex, mononegative N2O3 pentadentate in [Cu(H2L)(OAc)]·2H2O complex, mononegative N2O tridentate in [Cd(H2L)2]·H2O complex, and finally, neutral N2 bidentate in [Hg(H3L)(Cl)2]·2H2O complex. Coats–Redfern and Horowitz–Metzger methods were used to estimate the various thermodynamic and kinetic parameters. Cyclic voltammetry of the ligand in the absence and presence of Cd(II) and Hg(II) ions was studied. Fluorescence studies were performed in DMSO and showed that Cu(II) ions quench the fluorescence spectrum of the free ligand, whereas Cd(II) ions enhance it. The in vitro antimicrobial activities of the free ligand and its complexes against different bacterial strains and fungi Candida albicans were screened using agar‐disc diffusion techniques. The antioxidant potentials of the isolated compounds were also screened by employing SOD and ABTS free radical scavenging methods. Molecular docking studies were performed using Auto‐Dock tools to predict the best binding mode and predominant binding interactions.
For uranyl extraction, a distinctive chelating ligand, namely ethyl 2-amino-6-hydroxy-5-(4-methoxyphenyldiazenyl)-4-phenyl-4H-benzo[f]chromene-3-carboxylate, has been synthesized and characterized using FT-IR, NMR, and ESI-MS.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.