A salting-out homogeneous liquid-liquid microextraction was proposed for the quantification of four azole drugs in human urine prior to high-performance liquid chromatography analysis. The procedure involved the mixing of the sample with acetonitrile in appropriate volumes followed by the addition of sodium sulfate solution in order to facilitate phase separation. The parameters influencing the extraction performance were studied and optimized using a two-step experimental design. The analytical procedure was thoroughly validated using the accuracy profiles as a graphical decision-making tool.The β-expectation tolerance intervals did not exceed the acceptance criteria of ±15% meaning that 95% of future results will be included in the defined bias limits. The limits of detection of the procedure were satisfactory, ranging between 0.01 and 0.03 μg/mL. The mean analytical bias in the spiking levels was satisfactory and ranged between -10.3 and 4.2% while the relative standard deviation was lower than 5.6%. Monte-Carlo simulations followed by capability analysis were employed to investigate the ruggedness of the sample preparation protocol. The developed method offers advantages compared to previously reported approaches for the same type of analysis including extraction efficiency and scaling down of the sample volume and extraction time.
A palatal swelling in a child or adolescent may represent a neoplasm, such as a schwannoma and requires careful clinical and radiographic evaluation of the dentition.
Resorption of the alveolar crest, especially of the buccal plate, characterizes the healing extraction socket. Therefore, reduction of the vertical and horizontal dimension of the extraction site compromise the aesthetics and complicate rehabilitation. Alveolar Ridge preservation (ARP) has shown excellent results, minimizing the dimensional changes in order to facilitate an easier restoration especially when dental implants are used. The purpose of this poster is to present a series of 16 cases where ARP was performed with the use of dense-PTFE non-resorbable membrane in combination with different kind of bone grafting materials.
Background : Ameloblastic fibroma is a rare odontogenic tumor of mixed origin. Surgical removal of the lesion is necessary and often leads to large size three-dimension defects. Hard and soft tissue augmentation of these defects is challenging, and a combination of several surgical techniques can be utilized.Aim/Hypothesis : Purpose of this poster is to present the 3D augmentation of a large size vertical and horizontal defect in the posterior mandible after enucleation of ameloblastic fibroma 10 years ago on the same region.
Material and Methods: A 18-year-old male patient presented to the Postgraduate department of Oral and Maxillofacial Surgery of Athens Dental school, wishing rehabilitation with implants in the posterior right edentulous mandible. An ameloblastic fibroma had been surgically removed in the region 10 years ago in the same clinic and since the patient was under close follow-up. Clinical and radiographical examination revealed a huge hard and soft tissue deficiency in the posterior mandible, lack of the canine, premolars and molars and abnormal anatomy of
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