While denervation can occur with aging, peripheral nerve injuries are debilitating and often leads to a loss of function and neuropathic pain. Although injured peripheral nerves can regenerate and reinnervate their targets, this process is slow and directionless. There is some evidence supporting the use of neuromodulation to enhance the regeneration of peripheral nerves. This systematic review reported on the underlying mechanisms that allow neuromodulation to aid peripheral nerve regeneration and highlighted important in vivo studies that demonstrate its efficacy. Studies were identified from PubMed (inception through September 2022) and the results were synthesized qualitatively. Included studies were required to contain content related to peripheral nerve regeneration and some form of neuromodulation. Studies reporting in vivo highlights were subject to a risk of bias assessment using the Cochrane Risk of Bias tool. The results of 52 studies indicate that neuromodulation enhances natural peripheral nerve regeneration processes, but still requires other interventions (e.g., conduits) to control the direction of reinnervation. Additional human studies are warranted to verify the applicability of animal studies and to determine how neuromodulation can be optimized for the greatest functional restoration.
We present Bhās .ā citra, 1 a dialect mapping system for South Asia built on a database of linguistic studies of languages of the region annotated for topic and location data. We analyse language coverage and look towards applications to typology by visualising example datasets. The application is not only meant to be useful for feature mapping, but also serves as a new kind of interactive bibliography for linguists of South Asian languages.
South Asia is home to a plethora of languages, many of which severely lack access to new language technologies. This linguistic diversity also results in a research environment conducive to the study of comparative, contact, and historical linguistics-fields which necessitate the gathering of extensive data from many languages. We claim that data scatteredness (rather than scarcity) is the primary obstacle in the development of South Asian language technology, and suggest that the study of language history is uniquely aligned with surmounting this obstacle. We review recent developments in and at the intersection of South Asian NLP and historical-comparative linguistics, describing our and others' current efforts in this area. We also offer new strategies towards breaking the data barrier.
South Asia is home to a plethora of languages, many of which severely lack access to new language technologies. This linguistic diversity also results in a research environment conducive to the study of comparative, contact, and historical linguistics-fields which necessitate the gathering of extensive data from many languages. We claim that data scatteredness (rather than scarcity) is the primary obstacle in the development of South Asian language technology, and suggest that the study of language history is uniquely aligned with surmounting this obstacle. We review recent developments in and at the intersection of South Asian NLP and historical-comparative linguistics, describing our and others' current efforts in this area. We also offer new strategies towards breaking the data barrier.
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