Soft tissue calcifications are relatively common findings on panoramic radiographs (RP). However, by providing a two-dimensional view, the overlapping of anatomical structures in RP can make the diagnosis and localization of soft tissue calcifications difficult. By enabling a three-dimensional visualization and eliminating overlapping structures, cone beam computed tomography (CBCT) allows the identification of hyperdense images suggestive of soft tissue calcifications. The aim of this work was to identify and classify the maxillary-mandibular complex calcifications in RP and CFFC and to compare the findings in CFFC with those of the PR of the same patients. In this retrospective, observational and cross-sectional study, a calibrated examiner analyzed 53 pairs of RP and TCFC for the presence of calcification of the style-hyoid complex (CEH), tonsillolites, atheromas, sialolites, phlebolites, calcified lymph nodes and opacifications without defined diagnosis or foreign bodies. In 106 RP analyzes, 98 calcifications of the CEH, 6 tonsilloliths, 1 phlebolite, 1 sialolite, 5 calcified lymph nodes, 12 atheromas and no calcification "without diagnosis" were found. In 106 analyzes of CBCT, 99 calcifications of the CEH were found, 7 tonsilloliths, no phlebolite, 1 sialolith, 8 calcified lymph nodes, 9 atheroma and 1 "without diagnosis" calcification. RP and TCFC allowed the identification of soft tissue calcifications, however, their classification in RP was hampered by the overlapping of anatomical structures. When comparing the two types of exams, with CBCT as the "gold standard", PR was shown to be a sensitive test only for the diagnosis of CEH and lymph node calcifications when compared to CBCT and showed good specificity for all types of calcifications analyzed .