The presence of electron rich compounds such as amines added to the fluorescent methoxybinaphthalene boronic acid results in a dramatic increase in affinity of diols to the aryl boronic acid as well as in the augmented fluorescence response. This is likely the result of the change in boron geometry upon coordination with electron donor which facilitate the diols binding. Here, we demonstrate the role of amino alcohol additive in binding of saccharides by boronic acid‐based fluorescent sensor. We show that this strategy allows a poorly responsive sensor to become a highly sensitive probe for the detection of sugars, which could be used for classification of saccharides as well as for quantitative analysis in DMSO‐water solutions. The simple binaphthalene boronic acid sensor was particularly sensitive to d‐fructose (Ka=2.08×106), which allowed for identification of commercial sweetened beverages based on their d‐fructose content. The same method was successfully used for the quantitative analysis of d‐fructose in soft beverages.
Calix[4]pyrroles (CP) and polyammonium azacrowns (AC) are well-known receptors for anions. CPs bind anions by directional hydrogen bonds that do not always work well for aqueous analytes. The positive charge...
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