Background: The oral squamous cell carcinoma (OSCC) is the most common cancer worldwide and constitute a major health problem in developing countries, representing the leading cause of death. The oral cavity can be involved by a variety of lesions. These can be benign, premalignant or malignant. The most common carcinogenic agents associated with oral cavity lesions are tobacco, alcohol and betel nut (pan). Aims and Objectives: 1. early detection of premalignant and malignant oral lesions. 2. To conrm the cytological ndings by histopathological examination scrapped smear from 115 cases of oral cavity lesions were prepared and stained with MG Materials and Methods: G and PAP for cytological examination. The specimen/ biopsy material from oral cavity was collected, xed in 10% formalin and stained with H&E for Histopathological examination. July 2021 to June 2022. Out of 115 cases 23 were non- ne Study period: Results: oplastic, 22 cases were premalignant (dysplasia) and 70 cases were malignant in cytological examination. Overall, the scrape cytology diagnosis was concordant with nal histopathological diagnosis in 109 cases out of 115 cases with diagnostic accuracy 94.78%. The sensitivity was 92.11% and specicity was 100%. Oral scrape cytology is a rapid, painless, safe, inexpensive method for screeni Conclusion: ng and can diagnose a large number of patients in a short time. This method can be used for mass screening of population.
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