Introduction: Recently there is a surge of post COVID-19 MIS-C cases worldwide. Its diagnosis becomes challenging when a case presented with MIS-C like feature associated with scrub typhus infection. Method: Our cases presented with high fever, neurological and gasrtointestinal symptoms, rash and non-purulant conjunctivitis . All the cases have high inammatory markers like ESR,CRP,LDH,ferritin,IL6 with elevated D-dimer and CPK-MB in case 1 and 2. Echocardiographic abnormality was present in rst two cases and SARS-CoV-2 Ab was positive in all . Due to their MIS-C like presentation we treated with methyl prednisolone , IVIG, enoxaparin and oral aspirin but fever did not responded .Then after getting the Scrub IgM Ab positive and discovering eschar in third case we started doxycycline and the patients were discharged in stable condition. Conclusion: Tropical infections like scrub typhus may be associated with a post COVID-19 MIS-C like presentation.

Subacute sclerosing panencephalitis (SSPE) is a progressive neurodegenerative disease of children and young adults that may occur as an uncommon complication 7–10 years after a measles infection. In measles – endemic countries like India, the incidence of this fatal disease is high and more number of new cases are detected in recent times. In this case series, we have presented three cases of SSPE between the 4 and 5 years age group, presented with abnormal movement and neuroregression and diagnosed by characteristic clinical features, raised anti-measles antibody titer in CSF, and typical Electroencephalography findings. All of them had a history of measles infection before the vaccination and very short latency period between measles infection and the development of SSPE. They were discharged in stable condition after the treatment with oral Isoprinosine and intrathecal Interferon alfa 2b. Early age of presentation, short latency period, and apparently good response to treatment for the time being prompted us to present these cases.