A total of two hundred and thirteen (213) bacterial isolates were obtained gastrointestinal, urogenital and urinary tract specimens Specialist Hospital and Decent Laboratory in Kofar M The isolates were screened for the production of β method. β-lactamase production w lactamase production among Gram negative and G found to be 141(70.15%) and 5 (41.67%) respectively Haemophilus spp. 1(100%), Salmonella typhi 9(90%) were β (75.4%) and Klebsiella spp. 51 frequency of occurence. Among th and Enterococcus feacalis 1 (33.33%) showed
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