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Rates of tissue aging within an animal are coordinated through a complex network of intra-and intercellular signaling pathways.Due to the complexity of this multifactorial aging mechanism, a variety of molecular targets have been identified as age determinates across a number of model organisms ranging from yeast to primates (Kenyon, 2010). In multicellular organisms, the ability of these molecules to act across tissues and connect organ systems plays a critical role in animal physiology and age determination. The nervous

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