Background: Sucralfate is a basic aluminum salt of sucrose octasulphate which was orally taken for prevention and treatment of several gastrointestinal diseases. This study primarily aims to analyze whether sucralfate accelerates wound healing process in burn patients. The incidence of infection & relieve in pain in burn patients was also compared.Methods: This is an observational study carried out in the Department of General Surgery, Hamidia Hospital Bhopal on 50 patients divided into group 1 (sucralfate)and group 2 [a-sucralfate; b-silver sulfadiazine (SSD)]. Demographics, history, physical, and systemic examinations of the patients were recorded.Results: It was observed that sucralfate augments the formation of granulation tissue (in 6-17 days) as compared to SSD (14-22 days). It was noticed that faster healing by re-epithelialization was present in sucralfate group (11-22 days) as compared with SSD group (15-30 days). By the end of 3rd week 50-75% of wound was healed in sucralfate group as compared with 35-50% in SSD group. Incidence of secondary infection was less when topical sucralfate was used (group 1 = 25%; group 2a = 16.6%; group 2b = 66.66%). There was a marked relief in pain and discomfort after sucralfate application as compared to SSD.Conclusions: Using topical sucralfate expedite the burn wound healing process, significantly decreases pain with no local or systemic adverse reactions to the topical application therefore it can be used as an adjunctive or alternative agent in the future. However, multicentric trials with larger sample size are needed to insure the concept.
As the today’s world is concerned with speed and ease of the people , the need and growth of this aspects is also required in the application of the mobile development . This paper focuses on the android development technologies used in development of applications .In the growing world of technologies. During advancement of modern world applications have became a major part of everyone’s daily life . In todays life how complexity can be reduced is given more importance . There are various platforms which can be used for development of applications for windows , MAC , IOS, android ,etc. One of the popular one is Android Studio .Flutter is a framework like used for development of applications . It is open source SDK tool used for developing mobile applications for iOS and Android operating systems . The following paper describes the advantages of flutter tool over other development tools .
Background: Although the incidence of peptic ulcer disease has reduced, the peptic ulcer perforation rates remain constant. Till recently the emphasis has been placed on the identification of microbial flora associated with peritonitis caused by perforated peptic ulcer. The aim of this study was to determine the incidence and significance of intraoperative peritoneal fluid culture of fungus in patients with perforated peptic ulcers. Materials and method: In this study, we included 53 patients with intraoperatively confirmed perforated gastroduodenal ulcers admitted in our hospital. Patients were evaluated pre-operatively; intra-operative peritoneal fluid specimen was sent for culture & sensitivity; post-operative records of various parameters were studied; patients' morbidity and mortality were evaluated with reference to their culture outcome. Results: Fungal cultures of peritoneal fluid were positive in 24 out of 53 patients (45.2%), Candida being the most common isolated species in 22 patients (91.6%), followed by Apergillus. Fungal cultures were found positive more commonly in patients above 50 years of age and in females. Age, preoperative organ failure, delay in operation, high Mannheim Peritonitis Index (MPI) and Acute Physiology And Chronic Health Evaluation (APACHE) II scores, smoking, alcohol abuse, steroid use, H2 blockers and preoperative antibiotic therapy were risk factors for a positive fungal culture. MPI of 20 or more was statistically significant (p<0.001). Increased morbidity was observed in fungal peritonitis patients in comparison to non-fungal peritonitis cases. The Candida peritonitis group had a mortality of 18.18%, while the mortality in the non-Candida peritonitis group was 3.44%. Conclusion: Fungal positivity was a significant risk factor for adverse outcome in patients with a PPU. Patients with associated risk factors and a MPI score >24 and APACHE II score of >12 with positive intra-operative peritoneal fluid fungal culture can be considered for early antifungal treatment.
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