Gastrointestinal stromal tumours (GIST) account for less than 1% of gastrointestinal tumours, whereas Gastrointestinal autonomic nerve tumour (GANT) is a rare variant of gastrointestinal stromal tumour (GIST) and occurs at an estimated frequency of 1% of all malignant gastrointestinal tumours. We report the case of a 38-year old male which represents the rarity in the incidence of a Gastrointestinal Stromal tumour as well as the occurrence of a gastrointestinal autonomic nerve tumour together in the same patient which presented as a jejunal lump along with a terminal ileocecal intussusception. Multiple GISTs are associated with familial or hereditary syndromes are described only in few case reports whereas multiple sporadic GISTs have been rarely reported. This review aims to report the multiple sporadic occurrence of two types of GISTs as well as discuss highlight the features and prognosis of GANTs as surgeons and gastroenterologists are unaware of the existence of such an entity.
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