Bilayer tablets are the advanced form of conventional immediate release tablet system, which consist of either two similar or different drugs combined in a single dose for effective treatment of the disease improving patient compliance. However, the multilayer tablet technology is demanding It also necessitates meticulous selection of excipients and manufacturing conditions for each technological stage. The aim of this review is to provide an outline of state of art of bilayer tablet technology and emphasise the difficulties experienced during Bilayer tablet manufacturing along with its intend solutions for these challenges.
Keyword: Bilayer tablet, Conventional release, Challenges encountered, Compliance.
Extraordinary transmittance and focusing of light in quasi far field region using miniaturized optical devices is a daunting task. A polarization independent, broadband, planar metallic transmissive micro aperture capable of achromatically focusing visible light in quasi far field region is proposed. The calculated enhancement factor of transmission efficiency was about ~2.2. The total transmission after the aperture is about 60%. This high throughput focusing device will open new avenues for focusing electromagnetic energy in the wide area of sensors and energy concentration.
A self-quadruplexing antenna based on substrate integrated waveguide (SIW) is presented. A slot is engraved on its top surface of the SIW cavity, which generates four different resonant frequencies (around 6.54, 7.64, 8.30, and 9.60 GHz) when it is excited by four 50 Ω microstrip feed lines. Also, each resonant frequency can be controlled independently. Due to a quarter mode (QM) cavity, the antenna size becomes compact. The measured results show that the isolation between any two ports is more than 32 dB, and the estimated gain is more than 7.8 dBi at the operating frequencies. The proposed design is simple to fabricate, compact, and easy to integrate with the planner circuits.
This paper presents the time and frequency domain analysis of a compact tri-band notched UWB (ultra-wideband) antenna with integrated Bluetooth frequency for wireless applications. Modifications in radiating element and DGS techniques are used to achieve high impedance bandwidth. The antenna operates at UWB frequency band 3.1-10.6 GHz as well as Bluetooth frequency 2.4 GHz. The band notch characteristics are at Wi-MAX (3.3-3.7 GHz), WLAN (5-6 GHz), and X-Band Satellite communication (7.1-7.76 GHz). These notches are obtained by etching different slots in the ground plane and radiating elements. Gain, group delay, pulse transmission, and radiation patterns of the proposed antenna are also investigated. A prototype of the antenna is fabricated, and the reflection coefficient is measured. A comparison has been made between the proposed antenna and previously published UWB antennas.
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