Background: The relationship between psychiatric disorders and GI disorders such as IBS is well established. IBS patients typically suffer from depressive symptoms, which can aggravate their IBS symptoms. Objective: to quantify the prevalence of IBS and its association with depressive symptoms among the Riyadh general population. Methods: This cross-sectional study was conducted on Riyadh general population. The study included Saudi citizens, age was above 18 years old. Data were collected through personal interviews. Two self-administered and validated questionnaires were used. The first questionnaire is the Rome III criteria; a system developed to classify functional GI disorders (FGIDs), which are disorders of the digestive system for which clinical symptoms cannot be explained by the presence of structural or tissue abnormalities, the second questionnaire is the Patient Health Questionnaire (PHQ-9), a set of three self-report scales designed to measure the Major depressive disorder. Results: The prevalence of IBS, was 17.3%. 71.3% of cases had mixed (constipation and diarrhea) type, 5.3% had diarrhea predominant type and 23.4% had constipation predominant IBS. Most (73.4%) of the IBS cases were females. Among IBS cases, 20.2% had minimal depressive symptoms, 20.2% had major depression, mild severity. Major depression with moderate severity was found in 18.1% and major depression with severe severity was found in 28.7%. Family History of crohn's disease and stomach cancer were found in 17.0% and 92.6% of IBS cases respectively. Conclusion: A high prevalence of depression symptoms in our subjects emphasize the importance of the psychological evaluation of the patients with IBS, in order to better management of the patients and may also help to reduce the burden of health care costs.
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