BackgroundBrain training games (BTG) are believed to play a major role in improving cognitive functions. The current study evaluated if BTG showed positive impact on attention and memory functions compared with baseline visit in healthy subjects.Material/MethodsThe study was carried out from October 2015 until April 2016 in the Department of Physiology, College of Medicine, King Saud University and in King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia.We enrolled 51 normal healthy subjects to use a computerized cognitive training game (Lumosity) for exercises that target a range of cognitive functions, including attention, processing speed, visual memory, and executive functions for about 15 min per day, at least 7 days per week, for 3 weeks. The control (n=21) group did not perform the training. Both groups took the CANTAB test before and 3 weeks after training for various cognitive functions (flexibility, memory, attention, speed, and problem solving). Serum samples were used to study the brain-derived growth factor (BDNF) and apolipoprotein (Apo) E (APOE) levels.ResultsA significant improvement in Lumosity performance index was observed in the active group compared to the control group by the end of training (p-value 0.001). After the training, a statistically significant difference in most of the CANTAB measures, such as attention-switching task (AST), mean correct latency, AST switching cost, AST mean correct latency (congruent), AST mean correct latency (incongruent), AST mean correct latency (blocks 3 and 5) [non-switching blocks], AST mean correct latency (block 7) [switching block], and MOT mean correct latency (all P=0.000). However, in the control group, significant improvements were not observed. A positive correlation between pattern recognition memory (PRM) and APOE was found and people who had higher ApoE levels had faster response.ConclusionsAn improvement in different cognitive domains was noted, including attention and motor speed. However, this study warrants further research to determine the long-term effect on other cognitive functions and in different groups (e.g., elderly vs. adults).

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BACKGROUND Mobile phone use is become a popular in Saudi Arabia and one of the basics to live in the modern world. As It increase, there are some people will addict to it, and effect their life in many ways. Some of area that mobile phone use can affect us are; physically, socially, psychologically. Our aims of the current study are to know the incidence of mobile phone addiction in Saudi Arabia, how many hours they spend on it, most application used in Saudi Arabia, and any morbidity associated with the addiction. OBJECTIVE This study was designed to investigate the revised and short version of the smartphone addiction scale, also increase the awareness of mobile phone addiction among Saudi population, to know how the levels of education, and social interactions, can increase the risk to be addict for mobile phone and to see if addiction of mobile phone could increase risk for morbidity and mortality disease. METHODS This cross sectional, a set of questionnaires were provided to a total of 2004selected participants from from May 2018 to august 2018. The participants consisted of 1305boys and 699girls, and their average age was 18-25 years old. We use Test of Mobile-phone Dependence” (TMD) questionnaires. an online survey on twitter based study. Therefore, it will be coded, loaded and analysed by using Statistical Package for Social Science (SPSS ®️) program version (22.0) RESULTS Most of our population spends 5-8 hours on their phones (754, 37.6%). Interestingly, around thirty percent (592, 29.5%) spend more than 8 hours on their phones. CONCLUSIONS This study discovered that Saudi population are at risk of smartphone addiction and cause multi harmful consequences. However, targeted prevention and intervention strategies based on a multi-component strategy to decrease this behavioral problem in demanded.