Objective:The aim of the present study is to evaluate the use of autogenous particulated dentin mixed with platelet rich fibrin in surgically removed lower third molar socket. Materials and Methods: Sixteen patients (7 male and 9 female) were enrolled in the study. Their age ranged from 20 to 37 years. Patients were randomly divided into 2 groups. Group I, PD/PRF mix was grafted into the extraction socket. Group II, extraction socket was left without grafting. The CD, CAL and WAG of lower second molar were measured at 2, 4, 8 and 12weekes after surgery. MBL at the distal surface of lower second molar was evaluated at 1 and 6months after surgery. BD was measured at 6 month after surgery. Results: The PD/PRF mix group showed significant reduction of CD at the distal of lower second molar than the no grafted group. The PD/PRF mix group showed significant reduction of CAL at the distal of lower second molar than the no grafted group. The PD/PRF mix group showed significant less reduction of WAG at the distal of lower second molar than the no grafted group. The PD/PRF mix group showed significant less amount of MBL loss at the distal of lower second molar than the no grafted group. There was a significant increase of BD at the distal of lower second molar at 6 month in PD/PRF mix group than the no grafted group. Conclusion: Autogenous particulate dentin and platelet rich fibrin mix provided promising clinical outcomes and considered an ideal bioactive graft material for hard tissue regeneration. Autogenous particulate dentin and platelet rich fibrin mix assist healing and counteract pronounced resorption of alveolar process at the distal surface of second molar with preservation of the periodontium.
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