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Background: Ovarian tumors are a heterogeneous group of neoplasm that have become increasingly important now-a-days because of their large variety of neoplastic entities and gradually increased rate of mortality due to female genital cancers. Objectives: The aim of this study was to analyze the histopathological pattern and clinical presentation of malignant ovarian tumors according to the WHO classification of ovarian tumors [2003] in a tertiary care center of Dhaka, Bangladesh. Materials and Methods: This retrospective study included and studied a total of 54 cases of malignant ovarian tumors at the Department of Obstetrics and Gynecology, Popular Medical College Hospital, Dhaka, Bangladesh over a period of 3 years from Jan 2015 to Dec 2017. Results: The mean age was 47.44±14.24 years old (age ranged from 20-70 years). Of the 54 malignant ovarian tumors studied, the commonest histological pattern observed in the study was serous cyst adenocarcinoma constituting 26 cases (48.15%) followed by adenocarcinoma of ovary (25.9%), mucinous cyst adenocarcinoma (14.8%), endometriod adenocarcinoma (3.7%), dysgerminoma (3.7%) and ovarian choriocarcinoma (3.7%). High level of serum CA125 was found in most of the cases (n=48; 88.89%). The chief complaints were abdominal pain (n=38; 70.37%) and abdominal distension (n=29; 53.70%). Majority were admitted with less than one month duration of symptoms. The size of the tumor varied from 2.2 to 20 cm. All the patients were admitted in III and IV stage. Conclusions: Serous cyst adenocarcinoma was the common finding of this study. The prognosis and varying therapeutic strategies of malignant ovarian tumors necessitate an accurate histopathological evaluation. J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 100-105

Background: Iron deficiency anaemia is a common problem in antenatal patient especially in primigravida in developing world. The study was conducted to evaluate the efficacy of intravenous iron sucrose in antenatal primigravida anaemic cases. Aims and Objectives: The study was conducted to evaluate the response of intravenous iron therapy in anaemic antenatal primigravida patients. The rise of hemoglobin level was predicted after therapy. Materials and Methods: A prospective cross-sectional study was done in the antenatal clinic of Popular Medical College Hospital from January 2016 to December 2016. Primigravida women of e” 18 years with iron deficiency anaemia were included in this study. Pretreatment hemoglobin level was measured. After total dose of calculated iron, intravenous iron sucrose was infused to achieve the target hemoglobin. After completion of therapy hemoglobin was measured 2 weeks and 4 weeks after last dose of iron treatment. Mean, percentage, Chi-square test was done and P value <0.05 was considered significant. Results: Among the 63 primigravida anaemic patients mean age of the study subjects were 23.98 years with mean gestational age were 23.54 weeks. Their pretreatment hemoglobin level was 5.42 gm/dl. After total dose infusion of iron sucrose, the mean rise of hemoglobin after 2 weeks was 8.87 gm/dl and after 4 weeks was 10.87 gm/dl respectively. This findings were statistically significant (P<0.001). Attainment of target hemoglobin at the range of 9.1-11.0 gm/ dl was 50.79% and 65.08% after 2 weeks and 4 weeks respectively. Conclusion: Parenteral iron therapy in the form of iron sucrose proved to be better choice to correct iron deficiency anaemia in primigravida anaemic patients J Dhaka Medical College, Vol. 27, No.1, April, 2018, Page 79-82

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Background and Aims: During general anaesthesia, laryngoscope is a common equipment for intubation used by anaesthesiologists. Laryngoscope has been identified as a potential source of cross infection. Though guidelines exist for appropriate disinfection practices, recent reviews suggested that current methods of disinfection areless effective and compliance is poor with the established protocols. We conducted a questionnaire-based survey to study the current disinfection practices being followed by a cross section of anaesthesiologists. Methods: A simple questionnaire containing 14 questions was distributed amongst anaesthesiologists through online as well as direct contact. Data were analyzed with percentage analysis. Results: Out of 150 anaesthesiologists, 120 submitted the completed questionnaires. Residents constituted 41% and 46% were consultants. Eighteen (12%) used only tap water for cleaning and 132 (88%) used a chemical agent after rinsing with water. Out of 132, 76 (51%) used detergent/soap solution, 29 (19%) would wash and then soak in disinfectant or germicidal agents (glutaraldehyde, povidone iodine and chlorhexidine) and 18 (12%) would wipe the blade with an alcohol swab. With respect to disinfection of laryngoscope handles, 70% respondents said they used an alcohol swab, 18% did not use any method, 9% were not aware of the method being used, while 3% did not respond. Conclusion: Our results indicate wide variation in methods of decontamination of laryngoscopes. Awareness regarding laryngoscope as a potential source of infection was high. We need to standardize and implement guidelines on a national level and make available resources which will help to improve patient safety. CBMJ 2020 January: Vol. 09 No. 01 P: 04-10

Background: Patients with chronic renal failure on maintenance hemodialysis (MHD) have high risks of viral infections and the prevalence of transfusion transmissible viral infection is common among them. The aim of our study was to detect hepatitis B and hepatitis C virus in hemodialysis patients and healthy donors and to explore if there was a relationship between duration of hemodialysis and hepatitis B and hepatitis C in our patients. Methodology: A cross sectional study was conducted in a private hemodialysis clinic in Dhaka city with end stage renal disease on maintenance hemodialysis and an age matched healthy donors as comparable group from July 2015 to June 2016. Serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST), HBsAg and anti HCV were determined along with duration and units of blood transfusion needed by them. Results: Our study showed the mean age of 126 MHD patients were 42.2±11.7 years along with 132 healthy donors as control group had mean age 39.2±9.7 years. Among the hemodialysis patients 34 (26.98%) showed transfusion transmitted infection positivity and in control group 11 (8.33%) showed transfusion transmitted infection positivity with the difference between two study group showed statistical significance (p<o.oo1). History of blood transfusion showed the significant predictor of occurrence of TTV infection in hemodialysis patients (p<0.01). Duration of hemodialysis and seropositivity of TTI was not significant (p>0.05). The number of units of blood transfusion and the TTI positivity also showed no significant difference (p>0.05) with HBsAg (17.46%) and anti HCV (9.52%). Conclusions: The prevalence of TTI in hemodialysis patients is significantly higher than that in healthy individuals. So, the regular screening of HBV and HCV among patients and healthy donors are strictly provided to monitor the communicable disease. Bangladesh J Medicine July 2019; 30(2) : 78-82