In this study we describe 86 patients at the main hospitals of Arbil, Sulaimaniah and Dohuk provinces (the Autonomous Area) who in 1987 had surgically proven hydatid infection. Infection rate was higher in females than in males in the Sulaimaniah province, where as the opposite was true in Arbil and Dohuk provinces. Females were mostly housewives. Age ranged from 7 to 80 years, with the majority between 21-40 years of age. Most organs of the body were involved, especially liver, lung, peritoneum, spleen and other organs. The organ most commonly affected was the liver, followed by the lungs. Those having single organ involvement accounted for 83. 7o/o of patients, while 16.3% had multiple organ or site involvement by hydatid cysts.
The therapeutic and prophylactic effect of dehydroemetine and pentostam on Leishmania donovani in experimentally infected golden hamsters (Mesocricetus auratus) have been investigated. The intracardially infected hamsters with L. donovani and treated with dehydroemetine showed significantly lower weights in liver and spleen, and less in spleen length than those treated with pentostam. Dehydroemetine and pentostam failed to provide these animals with any protection against experimental infection with L. donovani when the drugs were administered prophylactically.
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