Novel metallophthalocyanines (M: Co, Cu, Ni) containing 2(2-methoxyphenyl)ethanol and 3-Hydroxybenzaldehyde groups were synthesized and characterized.The structures were confirmed by IR, UV/vis, 1H NMR, 13C NMR, mass spectroscopy  and elemental analysis. The aggregation behavior of these compounds was investigated in DMSO. In addition; the compounds 4-9 were investigated for anti-oxidant activities by super oxide radical; DPPH (2,2-Diphenyl-1-picrylhydrazyl); and hydroxyl radical scavenging assays; in which most of them displayed significant antioxidant activities. Furthermore; compounds 4-9  were evaluated for anti-inflammatory activity by indirect hemolytic and lipoxygenase inhibition assays and revealed good activity.
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