Prostate leiomyosarcoma is an extremely rare and very aggressive neoplasm that represents less than 0.1% of primary malignant tumors of the prostate. We present a patient with primary leiomyosarcoma of prostate and examine the cases reported in the literature to discuss the clinical, diagnostic and therapeutic aspects of this rare tumor. Median survival was estimated at 17 months (95% CI 20.7–43.7 months) and the actuarial survival rates at 1, 3 and 5 years were 68%, 34% and 26%, respectively. The only predictors of long-term survival were negative surgical margins and the absence of metastatic disease at presentation. A multidisciplinary approach is necessary for the proper management of this terrible entity.
Surgery with or without chemotherapy seems to be the main therapeutic method for operable leimyosarcomas, but in general there is no consensus on the best therapeutic approach. Most cases are diagnosed at an advanced stage of the disease. A global multicenter trial is needed to find therapies that would improve the prognosis.
Since December 2019, the COVID-19 pandemic has known a rapid and distressing spread. Little is known about the sexual impact on infected patients. However, several studies have reported a significant psychological impact on the population.The objective of our study is to assess the impact of the COVID19 pandemic on the sexuality of individuals who have been infected with the virus.Our study focuses on a population of 50 Moroccan patients initially declared to have COVID-19, using a multiple choice questionnaire on sexuality before and after infection with the virus. All participants were part of a couple in which at least one of the two partners had been infected with SARS-CoV-2.The results showed that all subjects were sexually active before their infection, of which 20% were dissatisfied with their sex life. At the time of our study, 78% of the recovered patients had not resumed sexual activity. 60% said they were anxious about having sex and 81% said the pandemic had altered their sex life. Only one patient reports an increase in libido and an improvement in the quality of orgasm. A couple reported having resumed sexual activity but with a change in their relationships.Anxiety and fear of infecting the other are major concerns, which affect the resumption of normal sexual activity and which sometimes lead to a change in sexual practices.
A new coronavirus outbreak has started since December 31, 2019. COVID-19 can cause multi-systemic infections of which respiratory complications are the most obvious symptoms. In this report, we will describe, for the first time, an unusual mode of disclosure of COVID-19 in a patient with symptoms of acute prostatitis, initially treated with antibiotic therapy and alpha-blocker. Faced with the worsening of the clinical picture and the appearance of respiratory signs in our current pandemic context, the search for corona virus by PCR on nasopharyngeal sample was carried out and proved positive in our patient.
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