Second trimester MPV and serum uric acid alone or in combination could be used as a useful biochemical markers for prediction of PE based on their validity, simplicity, and availability.

Improved maternal and fetal outcome in women with SLE has occurred following integrated multidisciplinary approach. This emphasizes the importance of postponing pregnancy when predictors of poor outcome are encountered.

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A total of 202 patients with clomiphene citrate (CC) -resistant polycystic ovary syndrome (PCOS) were randomly allocated into two arms of induction of ovulation; the first group (n = 102) received CC 100 mg and metformin 500 mg while the second group (n = 100) received letrozole 2.5 mg with ovulation rate, clinical pregnancy rate, adverse effects, and acceptability were assessed. Patients in the letrozole arm experienced higher rate of ovulation (82% versus 43.1%, p < .001), more dominant follicles (p < .05), better endometrial thickness (p < .001), higher clinical pregnancy rate (36% versus 9.8%, p < .001), higher multiple pregnancy rate (p < .05), lesser adverse effects (p < .05) and higher acceptability (p < .001) compared to patients in the CC and metformin arm. In conclusion; letrozole is better and more acceptable than combined CC and metformin for inducing ovulation in patients with CC-resistant PCOS with higher clinical pregnancy rate and unexpectedly higher multiple pregnancy rate.

The use of uterine packing to arrest PPH is simple, quick and safe procedure to avoid further surgical interventions and to preserve the fertility in low-resource setting.

Increased maternal age and body mass index together with NYHA class III-IV, significant pulmonary hypertension, reduced ejection fraction and development of heart failure during pregnancy are strong predictors of poor maternal and fetal outcome.

Objective: To assess the maternal and fetal outcome in pregnant women presented with acute appendicitis and to detect predictors of fetal loss. Methods:A prospective observational study included 118 pregnant women presented with acute appendicitis and divided into two groups, uncomplicated appendicitis group (n=64) and complicated appendicitis group (n=54). Operative details, maternal and fetal outcome were assessed. Univariate and multivariate analyses were used to detect predictors of fetal loss. Data was collected and tabulated.Results: Patients in the complicated group have gone midline incision, longer operative time, more postoperative fever, more surgical site infection, longer hospital stay (p<0.001), higher rate of abortion and fetal demise (p<0.05) than uncomplicated appendicitis patients. Conclusion:Poorer obstetric outcome was encountered in complicated cases. In addition to complicated appendicitis, the use of general anesthesia, operative time greater than 60 minutes, midline incision, postoperative pneumonia and hospital stay more than 3 days were other predictors of fetal loss. Larger studies are warranted to confirm or refute our findings.

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