Objectives:The objective of this study was to evaluate clinically and radiographically use of oxidized regenerated cellulose as a graft material in transalveolar sinus lifting and implant insertion. Subjects and methods: Eighteen implants were inserted in sixteen patients with missed upper molar teeth. They were divided into two groups: group A (study group) included patients who received dental implants after sinus lift with oxidized regenerated cellulose graft; group B (control group) included patients who received implants after sinus lift without graft. The patients were clinically and radiographically evaluated preoperatively and postoperatively immediate and 6 months post-surgery. Clinical evaluation included pain and discomfort, swelling and implant stability using osstell. Radiographical evaluation was done by CBCT to measure the bone height and density. Results: Both sinus lifted groups with or without graft have significant success rates with superior radiographic results of oxidized cellulose grafted group over non grafted one after a follow up period up to 6 months. Conclusion: Transealveolar sinus lifting with oxidized regenerated cellulose graft is a promising graft for sinus augmentation.