Four amino and organic acids, L-arginine, L-glutamic (as amino acids), ascorbic and salicylic (as organic acids) solution applied as soil drench in three concentration levels to evaluate for nematicidal effects against root-knot nematode, Meloidogyne javanica infecting sugarbeet. Their effects on sugarbeet yield and its components and quality parameters were determined. All of the tested compounds reduced the number of juvenile larvae in soil, immature stages, mature females in root, final nematode population as well as reproduction factor, comparison to the check treatment. These compounds were mostly variable in their effectiveness in reducing nematode infesting or reproduction factor and enhancing plant yield and quality according to compounds type and concentration level used. Then, the percentage of reduction in nematode parameters or/and the increases in crop parameters increased by increasing the concentration level of each tested compound. The ascorbic acid was more effective in reducing nematode fecundity, final nematode population and reproduction factor followed by salicylic acid, L-arginine acid and L-glutamic acid in a descending order. Also, the ascorbic acid component showed the best results in improving leaves, roots, sugar yields and quality parameters of sugarbeet in comparison with the other tested compounds. In comparing between the effects of both ascorbic acid and nematicide, Oxamyl on nematode development and reproduction factors as well as productivity of sugarbeet, the ascorbic acid recorded reduction in juveniles larvae in soil, final population number and reproduction factor with values of 76.3, 71.6% and 2.1 fold, respectively as well as increases in root yield and sugar yield with values of 65.73 and 126.51%, respectively, however, Oxamyl recorded reduction to 73.6, 77.3% and 1.9 fold in juveniles in soil, final population number and reproduction factor, respectively as well as increases to 68.09 and 124.12% in root and sugar yield, respectively. The problems associated with nematicides application turned the workers view to focus on new strategies or use new safe components or chemicals for nematode management program. On the other hand, it was obvious from the obtain data, the