Background; Congenital anomalies are present in 2-4% of newborns and are an important cause of fetal and neonatal mortality and morbidity, Aim and objectives; to compare magnetic resonance imaging to ultrasound in detection of congenital fetal malformations, Subjects and methods; Our prospective randomized control study to compare magnetic resonance imaging to ultrasound in detection of congenital fetal malformations. The was carried out on 100 pregnant women at second and third trimesters who were divided into two equal groups: group A (cases) comprised fetus with congenital anomalies on ultrasound examination and group B (control Group): low risk pregnancies with no detected fetal anomalies on ultrasound examination, Result; Four of patients were diagnosed with congenital anomalies detected by prenatal MRI that differed from that of postnatal diagnosis which represented 8% of all cases and 46 of those cases were diagnosed as same as postnatal diagnosis which represented 92% of all cases. There was no significant difference between prenatal MRI and postnatal diagnosis in detection of prenatal congenital CNS anomalies with p value was 0.123, Conclusion; Fetal MRI has a superior diagnostic accuracy.
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