A novel series of six nonionic polymeric surfactants were prepared by polymerization of acrylated poly(ethylene glycol) (PEG, molecular weight MW = 400, 600 and 2,000) and allyl ester of long chain fatty acid chloride (decanoyl and lauroyl chloride). The unique structural features of these surfactants were confirmed by different spectroscopic tools (IR and 1 H NMR). The surface properties of these compounds such as surface tension, interfacial tension, emulsion stability, wetting power, foam height, solubilization and dispersant properties in disperse dye systems were determined and evaluated. A comparison study was done between the chemical structures and surface properties of such compounds. Biodegradability and stability to hydrolysis in acidic and alkaline media were also determined and evaluated.
In order to obtain peptide based surface active agents with antimicrobial activity, a series of polyethylene glycol bounded peptide chains were synthesized (I-VI). The investigated peptide chains contain aliphatic and aromatic amino acids in different sequences. These compounds were prepared by use of liquid phase method loaded on polyethylene glycol with molecular weight 3000 Daltons as a polymeric support. The produced target peptides were characterized by means of their amino acid analysis, HPLC and UV spectroscopy. The physicochemical, surface active properties measurements and in vitro antimicrobial activity of the synthesized peptide chains were evaluated. The synthesized peptide chains were found to have promising surface properties beside their antimicrobial activity.
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