Prostate cancer is the most common non skin cancer in men. Screening for prostate cancer with prostate specific antigen (PSA) may help in decreasing morbidity and mortality of men.to assess the PSA level among Iraqi men in Al-Anbar governorate. Hundred and sixty two patients with prostate cancer as a study group and fifty apparently healthy subjects as a control group were included in this study from the period of 1 st of June, 2007 to 1 st of October, 2010. All the patients were well diagnosed clinically and by laboratory investigations by their physicians and they were on therapy. Blood samples were taken from both the study and control groups and tested for detection of PSA levels. All PSA measurements were performed in the laboratory using ELISA test. A significantly higher percentages of patients with prostate cancer had a PSA level of more than 4.0 ng/ml (79.6%) than those among apparently healthy subjects (16%)(p<0.05). Men from older age groups had higher percentage of PSA level of ≥ 4.0 ng/ml than in younger age groups. Men with older age group are more exposed to risk of prostate cancer and should be encouraged to participate in early detection studies to define personalized PSA screening that may diagnose prostate cancer at a curable point.
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