Background: During this pandemic everyone is facing the wrath of this novel coronavirus but nurses who are meticulously working in closed contact with diseased are at more risk for developing anxiety, depression and compromised quality of life. This study was conducted with an intent to identify anxiety, depression and quality of life and its predictors among nurses who are actively involved in caring of COVID-19 patients. Methods: A cross-sectional online survey was carried out among nurses who were actively involved in COVID-19 duties at government tertiary health care institutes of India and data was collection through convenience sampling. Standardized tools (HADS, WHOQOL-BREF) were preferred for the assessment of participants' anxiety, depression and quality of life. Multivariate regression analysis was used to identify predictors for anxiety and depression. Results: Of 354 nurses, 12.1% were suffering from anxiety while 14.7% had depression. Mean score for physical, psychological, social and environmental domains were 14.75 ± 1.86, 14.92 ± 2.46, 15.21 ± 3.01, and 14.48 ± 2.38 respectively. Nurses' education was a significant predictor for anxiety (odds ratio [OR] = -0.262, 95% CI: -0.510- -0.014, and P value = 0.038). Similarly for depression, designation of nurses acts as a contributing factor (odds ratio [OR] = 0.287, 95% CI: 0.016- 0.557, and P value = 0.038). Conclusion: Nurses are providing their services beyond boundaries so that we can overcome with hard time of COVID-19 pandemic. Although less but still nurses are suffering from anxiety and depression which need to be addressed to protect and enhance their mental well-being.

Background: Nursing is a very challenging profession, which requires very stringent training since initial years of nursing education. Throughout the training period, students are exposed to various stressful situations. Inability to cope up with varied stressors may lead to psychological distress and impede students' pursuits of nursing career. Objectives: The aim of the present study is to assess stress and coping strategies among nursing students of Western Rajasthan. Materials and Methods: Two hundred and twenty-one undergraduate nursing students were recruited for the study through total enumeration. Standardized Student Nurse Stress Index and brief cope scale were used to assess stress and coping strategies. Results: Nearly 82.4% of the students reported moderate level of stress. Interface worries (mean score 17.88 ± 4.9) and academic load (mean score 17.6 ± 4.78) were the major source of perceived stress. Students considered attitude of other professionals toward nursing, lack of free time, and fear of examination as most likely reasons of their distress. Active coping was the most commonly used coping strategies. Level of stress was found to have significant association with the interest of students in nursing. Conclusions: Interface worries and academic-related concerns emerged as major source of stress. A positive trend was evident in the use of adaptive coping strategies over succumbing meekly. However, there is a great need to plan and implement stress management programs so that these budding health professionals could be better equipped and trained to face various challenges of the profession.

Introduction: The COVID-19 Pandemic has caused anxiety and stress among people. Nursing students, being an important link in the delivery of health care services, are always exposed to stressful situations which in turn put a great toll on their mental health. Moreover, the perceived risk of pandemics motivates people to embrace different protective measures so as to reduce any potential threats of an emerging health concern. Objective: The aim of this study was to assess the COVID-induced anxiety and protective behaviors among nursing students. Methods: Nursing students studying at 02 nursing institutes of Jodhpur, Rajasthan, India were enrolled for the study. The data were collected using COVID-induced anxiety scale and protective behaviors towards COVID-19 Scale. These scales were converted to online google forms, and the link was circulated among 370 nursing students through emails and WhatsApp. A total of 229 students submitted their responses within stipulated time and were included in the final data analysis. Results: The response rate of the survey was 62%. Evidently, nursing students had a moderate level of anxiety (mean score 31.28 ± 5.29) due to the COVID-19 outbreak. Overall protective behavior mean score was 56.63 ± 6.4 which reflects that students were following higher quality of protective behaviors. There is a negative linear correlation between anxiety score and protective behavior score. Conclusion: The nursing students exhibited a moderate level of anxiety, and routing protective behaviors were frequently performed by these students. There is a timely need to plan and implement interventions for nursing students so as to make them self-capable to resolve psychosocial issues, especially during disease outbreaks.

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Adolescents are highly vulnerable to psychiatric disorders. This study aimed to explore the emotional and behavioral problems in adolescents. A community-based exploratory survey was conducted between November and December 2019. Cluster sampling was done. 300 adolescents in12 to 18 years of age group from the different randomly related areas of Jodhpur city were involved in the study. Emotional and behavioral problems were assessed by using a self-structured Emotional and behavioral problem questionnaire. Inform consent and assent were taken before filling the questionnaire Descriptive and inferential statistics were applied for analysis. SPSS version 16 was used for data analysis.Emotional problems are more prevalent in the population. Nearly 41% of participant falls under the borderline category and 1.33% i.e. 4 participant falls under the severe category comparatively behavioral problems are less prevalent. 21.66% of participant has a borderline level of behavioral problem and only one participant was found to have a severe level of behavioral problem. The domains under emotional problems have a higher mean value than the domains under behavioral. A number of siblings are significantly associated with behavioral problems. Emotional problems are more prevalent than behavioral problems. These data suggest that there is a need for mental health services for adolescents.

The objective of the study were to develop the guidelines for caretakers of HIV/AIDS patients on prevention and home care management of opportunistic infections; evaluate the effectiveness of guidelines on prevention and home care management of opportunistic infections for caretakers of HIV/AIDS patients before and after administration of guidelines in terms of knowledge of caretakers; seek the association of post test knowledge scores of caretakers on prevention and home care management of opportunistic infections with selected demographic factors; determine the acceptability and utility of guidelines on prevention and home care management of OIs by the caretakers of HIV/AIDS patients. An evaluative research approach with one group pre-test post-test design was adopted for the study. The study was conducted in Ram Manohar Lohia Hospital, New Delhi. The sample consisted of 60 caretakers of HIV/AIDS patients selected by purposive sampling. The tools used were structured interview scheduled and a structured opinionnaire. Guidelines were developed for enhancing the knowledge of caretakers regarding prevention and home care management of opportunistic infections among HIV/AIDS patients The data obtained were analyzed using both inferential and descriptive statistics. The major findings of the study were that the mean post-test knowledge scores were higher than mean pre-test knowledge scores of caretakers indicating that the guidelines were effective in increasing the knowledge of caretakers regarding prevention and home care management of opportunistic infections among HIV/AIDS patients. There was significant association of post-test knowledge scores of caretakers regarding prevention and home care management of OIs with selected factors-age, sex, educational qualification, marital status, occupation, family Income. The structured opinionnaire revealed that the guidelines on prevention and home care management of OIs were acceptable and useful for the caretakers.

RESULTS:We included 10 RCTs which met the eligibility criteria. According to the analysis of best treatment, anidulafungin had the highest probability (0.46) of global response, followed by micafungin (0.41), and also demonstrated statistical difference with fluconazole (DR -0.18, 95%CrI -0.29-(-0.08)). Anidulafungin had less allcause mortality compared with amphotericin B deoxycolate (AmpB)(DR 0.12, 95%CrI 0.03-0.24), micafungin (DR 0.20, 95%CrI 0.03-0.37) and caspofungin (DR 0.17, 95%CrI 0.04-0.34). Related to safety events, anidulafungin had less hepatotoxicity than fluconazole (DR 0.08, 95%CrI 0.01-0.23). No significant differences in nephrotoxicity between the treatments was found due to heterogeneity, however, there was a possible clinical difference between anidulafungin and AmpB (DR 0.26, 95%CrI -0.03-0.92). The quality of the evidence was moderate to low in the majority of the outcomes mainly due to risk of bias and imprecision. CONCLUSIONS: The network meta-analysis suggests that anidulafungin may be an effective and safe treatment for IC when it is compared with other available antifungals.

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