Current systems are perfectly 'designed' to produce their current results" (Fixsen, Blase, Metz, & Van Dyke, 2013, p. 224). This adage implies that the outcomes generated by programs are a function of the practices implemented by those programs. For many students with autism spectrum disorder (ASD), high school programs often lead to unemployment, inactivity, continued residence with the family in adulthood, and social isolation, especially if those students have severe impairments and/or are from low-income families (Shattuck et al., 2012). While these outcomes are influenced in part by factors operating outside of the schools' control (e.g., lack of ongoing support in the community), this does not absolve researchers or educators from the responsibility for post-school outcomes. It is also important to note that the poor outcomes following years of schooling are not intentional. Teachers and service providers wish the best for teenagers with ASD and work hard to achieve positive effects. But for many teenagers with ASD and their families, independence, social integration, and employment after high school can be elusive (Test, Smith, & Carter, in this special issue).An active research literature on interventions and instructional approaches exists for children and youth with ASD. However, most comprehensive treatment models (Odom, Boyd, Hall, & Hume, in press) and focused intervention practices (Wong et al., 2013) have been conducted with preschool-and elementary-school-aged children. To date, few programs have been designed specifically for adolescents with ASD in high school settings.Moreover, the complexity surrounding high school programs and students with ASD make introducing and supporting change in practice a wicked problem. Fixsen et al. (2013) described wicked problems as "those that are difficult to define and that fight back when you try to solve them" (p. 218). There is probably no more wicked a 519826R SEXXX10.