In an effort to prepare small molecule mimics of the
active site
of lytic polysaccharide monooxygenase (LPMO), three monoanionic tridentate
N donor ligands comprising a central deprotonated amide group flanked
by two neutral donors were prepared, and their coordination chemistry
with Cu(I) and Cu(II) was evaluated. With Cu(I), a dimer formed, which
was characterized by X-ray crystallography and NMR spectroscopy. A
variety of mononuclear and dinuclear Cu(II) species with a range of
auxiliary ligands (MeCN, Cl
–
, OH
–
, OAc
–
, OBz
–
, CO
3
2–
) were prepared and characterized by X-ray diffraction
and various spectroscopies (UV–vis, EPR). The complexes exhibit
structural similarities to the LPMO active site.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.