Background: In pre-eclampsia, there is increased uteroplacental resistance and reduced foetal perfusion due to inadequate invasion of spiral arterioles by trophoblast cells. This causes impaired foetal growth and foetal hypoxia. To assess the usefulness of foetal Doppler in predicting adverse perinatal outcome in preeclampsia.Methods: All the women with preeclampsia from 30 weeks onwards were enrolled in the study. The umblical artery (UA) Systolic-diastolic (S/D) ratio >2 standard deviation (SD) or UA - Pulsatility Index (PI) and UA - Resistive Index (RI) >2 SD were taken as abnormal. The middle cerebral artery (MCA) was visualised and cerebroumblical PI ratio calculated. MCA-RI <2SD was taken as abnormal.Results: There were 107 women in the study. Major adverse outcomes 11. Umbilical artery - S/D ratio >2SD (RR 4.46, 95%, CI 1.40-14.17) and RI >2SD (RR 3.36, 95%, CI 1.03-10.61) and MCA RI <2SD (RR 4.46, 95% CI 1.4-14.17) had a high relative risk to predict adverse major perinatal outcome. 39 babies were admitted in neonatal nursery and no parameters could predict them. Though UA - PI >2SD predicted acute foetal distress in labour (RR 2.33, 95% CI 1.21-4.47), there was no association on multivariate regression analysis.Conclusions: This study showed UA-S/D ratio and UA-RI >2SD are significant predictors of perinatal deaths and immediate neonatal resuscitation in preeclampsia. Acute foetal distress in labour or neonatal nursery admission could not be predicted.
Background: Maternal death has a serious implication on the family, society and nation. The preventable and avoidable factors have been noted in most of the maternal deaths and these can be reduced by effective and affordable actions. The objective of present study was to evaluate the causes of maternal mortality in a tertiary care hospital, assess its epidemiological aspects and suggest remedial measures to reduce the same.Methods: A retrospective study of all hospital records and death summaries of all maternal deaths over a period of 16 months from April 2015 to July 2016 was carried out and epidemiological factors and causes affecting maternal mortality were assessed.Results: A total of 100 maternal deaths occurred over a period of 15 months out of which unbooked and late referrals constituted 75.55 % of maternal deaths. Most maternal deaths occurred in the age group of 20–30 years, multiparous women (73%) and women from rural areas (71.%). Direct obstetric causes were responsible for 91 maternal deaths whereas 50 maternal deaths were due to indirect causes. Most common cause of death (41) was hemorrhage, followed by pregnancy-induced hypertension including eclampsia (15) and sepsis (21).Conclusions: Hemorrhage, sepsis and hypertension including eclampsia were seen as the direct major causes of death. There is a wide scope of improvement because a large proportion of the observed deaths are preventable.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.