Metal–organic frameworks (MOFs) have attracted a great deal of attention in the areas of biomedicine due to their versatile porous structures and are potentially ideal vehicles for loading bioactive molecules and controlling the release of small molecules. Current approaches for encapsulation of drug molecules in MOFs are usually based on multistep wet processes. We report here a novel simple and rapid solid‐state process that combines the mechanosynthesis of HKUST‐1 and the encapsulation of ibuprofen (IBU‐H), as a model drug molecule, in a one‐pot reaction involving a pre‐assembled [Cu2(IBU)4]·2DMF cluster. The ibuprofen‐loaded MOF composite (with 58.5 wt.‐% loading capacity) was also studied as a drug delivery carrier system in phosphate buffered saline (PBS) solution at 37 °C.
Lighting technologies developed significantly in the last decade. New LED light sources, dedicated luminaires and improved lighting control techniques gave rise to new possibilities in improving energy efficiency of lighting solutions. The article is an overview of interior, road and exterior architectural object lighting design strategies. It also presents design considerations that directly impact lighting conditions and energy efficiency. Practical examples of the application of basic design strategies, accompanied by the obtained energy results, are also depicted. Issues discussed in the article may be useful in researching and designing interior and road lighting, as well as f loodlighting. They can also be useful in planning and implementing strategies aimed at improving lighting conditions and energy efficiency of lighting solutions.
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