268ChemInform Abstract The reactions between the ferrocenylcarbinols (I) and the 5-aryltetrazoles (II) in glacial AcOH proceed regiospecifically to yield the 2-ferrocenylalkyl derivatives (III) as the sole products. The structures of the ferrocenylcarbinols and the electronic nature of the aryl group of the tetrazoles (II) have no influence on the outcome of the reactions. The reactions are believed to occur between ferrocenylcarbonium cations formed under the acidic conditions and tetrazolate anions. This assumption is confirmed by further experiments. Inan analogous manner the bis-hydroxyalkylferrocenes (IV) yield the bis-2,2'-tetrazoloferrocenes (V) on reaction in glacial AcOH.
The reaction of the ferrocene alcohols (I) with the tetrazoles (IIa) and (IIb) yields mixtures of the corresponding Z‐substituted (III) and 1‐substituted tetrazoles (IV), whereas the nitrotetrazole (IIc) gives only the 2‐substituted derivatives (IIIc).
Durch Umsetzen der Ferrocenylcarbinole (I) mit den Harnstoffderivaten (II) in Essigsäure und nachfolgendes Verdünnen mit Wasser werden die Titelverbindungen (III) erhalten.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.