Dietary inclusion of a water‐soluble fraction of blue mussel Mytilus galloprovincialis was examined as a feeding stimulant for juvenile Japanese flounder Paralichthys olivaceus. The control diet mainly consisted of fish meal, potato starch, and pollack liver oil. Five, 10, and 20% (weight/weight) of the control diet was exchanged with aqueous extracts of blue mussel meat in experimental groups. Fish of about 10 g in initial body weight were fed each diet to satiation, twice daily, 6 d per wk for 6 wk at 20 C. The final body weight, weight gain, and feed efficiency of fish fed the diets containing blue mussel extracts were significantly higher than those of fish fed the control diet. However, these parameters were not different among experimental groups containing blue mussel extract independent of the inclusion level of extract. A similar trend was shown in protein efficiency ratio as fish fed the control diet had a significantly lower protein efficiency ratio than the other dietary groups. Compared to the control diet, higher plasma protein and lower triglyceride were found in fish fed the diets with the extract, while other blood constituents were relatively similar for the dietary groups tested. On the other hand, whole‐body crude lipid content and lipid retention of fish fed the diets with the extract were generally significantly higher than those of fish fed the control diet. Whole body crude protein was identical regardless of the dietary composition; however, protein retention of fish showed a similar trend to lipid retention.

The patient was a 74-year-old male. (History) The patient had been experiencing left papillary hematogenous secretion for approximately 3 years. He had been neglecting it for some time, but when he began to notice persistent secretion, he came to our clinic.(Present condition) On physical examination, no mass was palpable, and only bloody nipple discharge was observed. Mammary ultrasonography showed a hypoechoic mass of approximately 8 mm in size in the left nipple. A needle biopsy was performed, a diagnosis of invasive ductal carcinoma was made, and a thoracic muscle-sparing mastectomy and sentinel lymph node biopsy were performed. Histopathological findings showed a diagnosis of invasive ductal carcinoma: tubule-forming type, pT1aN0M0 stage I, ER (+), PgR (+), HER2 score 1, and ki67 30%.(Discussion) Male breast cancer accounts for approximately 1% of all breast cancers. The initial presentation is often palpable as a painless mass. Noninvasive ductal carcinoma is common, although bloody papillary discharge may be present, and invasive ductal carcinoma may be advanced. We report this case because it was treated early and the patient had a good course.