The design and application of a simple capsule administration tube for miniature capsules are described. Experiments with rats have shown that the tube is capable of depositing capsules at the distal end of the oesophagus. Regardless of the location of the capsule in the oesophagus, provided normal peristaltic action occurs, the capsule will have reached the stomach and discharged its contents within 10 min. After a short training period of 3-4 days the insertion of the tube does not appear to cause the rats undue discomfort, nor does it cause tissue damage. The procedure, which can be performed rapidly by 1 technician, is ideally suited for dispensing solid materials to fully conscious animals.
A new method of dorsal arthrodesis in patients with atlanto-axial instability of different etiology is described. In three patients solid laminar osteosynthesis C1/C2 was achieved by insertion of an autogenous cortico-cancellous bone graft into the interlaminar space and by a bilateral application of the lately developed metal clamp. The technical principles of the clamp guarantee a permanent pressure on the graft and a solid initial stability in the segment. Additional external fixation and immobilization of the patient are not necessary. Complications as known from other procedures of the atlanto-axial dorsal fusion will be prevented efficiently.
A new surgical procedure for treatment of congenital, symptomatic atlanto-axial instability (os odontoideum ) is described. Two metallic clamps, with an integrated inner spring for maintaining continuous pressure on a cortico-cancellous bone-graft implanted into the interlaminar space, are fixed posteriorly on the vertebral arches C1/2 next to the graft. Because of the initial solid segment-stability external fixation is unnecessary. Posterior interlaminar osteosynthesis prevents late neurological complications caused by a mobile os odontoideum .
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