Biomarkers, which can be obtained from different sources including blood, tissues, body fluids, and urine, can be evaluated to indicate normal, pathogenic, or therapeutic response to biological system. Early detection of biomarkers not only prevent the spread of infectious disease but also drastically decrease the death rate of people suffering from different diseases, especially in rural areas where financial resources are limited. Low cost microfluidic technologies have applications in human health diagnosis, food safety, and environmental analysis. This article briefly reviews different kinds of microfluidic platforms including paper, polymer, and hybrid platforms as a microfluidic biosensor for the detection of disease biomarkers. It also discusses the current limitations and future prospects.
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