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OBJECTIVEDetermine gender-related differences and risk factors for death and events, both in-hospital and at six-month evolution, of patients admitted within the fi rst twelve hours of ST-segment elevation acute myocardial infarction and who underwent primary percutaneous coronary intervention. METHODSBetween July 1998 and December 2000, 199 consecutive patients were enrolled in the study, with elevation myocardial infarction and without cardiogenic shock, outcome, in-hospital and six-month progression were studied. RESULTSClinical characteristics were similar in both groups, except that women were older than men (67.04 ± 11.53 x 59.70 ± 10.88, p < 0.0001). In-hospital mortality was higher among women (9.1% x 1.5%, p = 0.0171), as was the incidence of major events (12.1% x 3.0%, p = 0.0026). The difference in mortality rates remained the same at six months (12.1% x 1.5%, p = 0.0026). The multivariate analysis predicted death: female gender and an age over eighty years, and major events and/or stable angina multivessel: disease and severe ventricular dysfunction. CONCLUSIONFemale gender and an age over eighty years were independent predictors of mortality, six months of patients who had undergone primary percutaneous intervention. KEY WORDSPrimary coronary angioplasty, acute myocardial infarction, gender, risk factors.

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