<p><strong>Background:</strong> The aim of the work was a prospective study of utilization review for multiple antibiotics prescribed in the specialty department in a tertiary care teaching hospital.</p><p><strong>Methods: </strong>A prospective study was conducted for 6 months in specialty department in a tertiary care teaching hospital.</p><p><strong>Results: </strong>In the 6 months duration of the study, a total number of 96 prescriptions were analyzed. The 77 prescriptions were prescribed with Beta-lactam antibiotics. and remaining prescriptions were prescribed with 2, 3 and 4-5 different classes of antibiotics.</p><p><strong>Conclusions: </strong>The result obtained from our study is for judgment use of antibiotics will reduce the burden of multi-drug resistance and thereby enable better patient management and limit patient morbidity and mortality.<strong></strong></p>
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