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The basis of the proposed method is the information-capacity phenomenon of a drying drop -the kinetics of a selforganization process, which, in the same environment, is determined solely by the composition and inner structure of the liquid. A drop of tested liquid of volume 5 µl dries up on the surface of a quartz resonator oscillating with ultrasound velocity. We examine the shear characteristics of a drop, which are extremely sensitive to the occurrence and rise of new-phase structures. The measured quantity is the acoustic-mechanical impedance (AMI) of a drying drop, and the drying dynamics is displayed in the form of two curves, corresponding to the real and imaginary parts of AMI. Their shape is an ID characteristic of the liquid under the same conditions of temperature and humidity. The drying process, represented in the phase plot or in the phase space, changed under the action of external physical factors, such as ultraviolet irradiation, magnetic field, different smells, and dissolvent adding. The relaxation time and solution memory were demonstrated, using salt, protein-salt solutions, and multi-component liquids of different nature.

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The dynamical characteristics of integral mechanical properties of drying droplets of blood serum, urine and saliva were studied by measuring the acoustic-mechanical impedance (AMI) using a computer-controlled setup described earlier. The method is based on the following idea. When a 5µl liquid drop is drying on the surface of a quartz resonator plate oscillating at a constant frequency (equal to the resonance frequency of an unloaded resonator, 60 kHz), there arises a shear wave highly sensitive to the formation and growth of a new phase at the liquid-quartz interface. The experimental setup measures a change in the complex electric conductivity of the liquid-quartz system, calculates the parameters of the AMI dynamics in the drying drop, and displays their variation on the monitor at the real time scale in the form of a curve. At a time the optical properties of drying drops were observed. For each disease or a physiological state the geometrical features of the curves were extracted and then the shape indices were calculated. In the cases under study each "pathology" group differed from the "norm" by its specific shape index, by which diseases of other nature did not differ. Possible mechanisms behind formation of the morphological and dynamical differences in drying drops of biological liquids of healthy and sick people are discussed.